AagingBase: Database of anti-aging peptides
A manually curated comprehensive database for anti-aging peptidesThe Literature info page of AAPeptide gives experimental informations of anti-aging peptides of AagingBase that were collected from scholarly articles and patents. Users can find the data in a filterable and sortable table. To obtain further details, refer to the Help page.
| AAP_ID | Reported name | ID | Year | Origin | Source | Experiment type | Cell lines/Animal model | Condition addressed | Bioactivity |
|---|---|---|---|---|---|---|---|---|---|
| AAPeptide021 | Pep-WH-1 | US 2018/0134749 A1, EP 3305802 A1 | 2018 | Synthetic | NA | In vitro | THP-1, HepG2 | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide022 | Pep-WH-3 | US 2018/0134749 A3, EP 3305802 A1 | 2018 | Synthetic | NA | In vitro | THP-1, HepG2 | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide023 | Pep-WH-2 | US 2018/0134749 A2, EP 3305802 A1 | 2018 | Synthetic | NA | In vitro | THP-1, HepG2 | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide024 | Pep-WH-4 | EP 3305802 A1, US 2018/0134749 A4 | 2018 | Synthetic | NA | In vitro | THP-1, HepG2 | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide025 | Pep-WH-6 | US 2018/0134749 A6, EP 3305802 A1 | 2018 | Synthetic | NA | In vitro | THP-1, HepG2 | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide026 | Pep-WH-11, Pep-WH-5 | US 2018/0134749 A11, EP 3305802 A1 | 2018 | Synthetic | NA | In vitro | THP-1, HepG2 | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide027 | Pep-WH-10 | EP 3305802 A1, US 2018/0134749 A10, US 10676507 B2 | 2018,2020 | Synthetic | NA | In vitro, In vivo | Human acute monocytic leukemia cell line (THP1), HepG2 cell line, Sprague-Dawley (SD) rats | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide028 | Pep-WH-12 | US 2018/0134749 A12, EP 3305802 A1, US 10676507 B2 | 2018,2020 | Synthetic | NA | In vitro, In vivo | Human acute monocytic leukemia cell line (THP1), HepG2 cell line, Sprague-Dawley (SD) rats | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide029 | Pep-WH-7 | EP 3305802 A1, US 2018/0134749 A7 | 2018 | Synthetic | NA | In vitro | THP-1, HepG2 | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide030 | Pep-WH-9 | EP 3305802 A1, US 2018/0134749 A9 | 2018 | Synthetic | NA | In vitro | THP-1, HepG2 | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide031 | Pep-WH-8 | EP 3305802 A1, US 2018/0134749 A8 | 2018 | Synthetic | NA | In vitro | THP-1, HepG2 | Skin aging | Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition |
| AAPeptide032 | NA | US 2018/0325794 A1, EP 3366694 A1, US 10478392 B2 | 2018,2019 | Natural | Human | In vitro | Human epidermal keratinocytes | Skin aging | Inhibites skin-wrinkle formation |
| AAPeptide033 | AtgPep-1 | US 2018/0002380 A1 | 2018 | Synthetic | NA | In vitro | A549, HT1376, MDA-MB-231, HeLa cells, BEAS-2B | Age related autophagy-related diseases | Effective in detecting and imaging autophagy in vitro and in vivo |
| AAPeptide034 | AtgPep-3 | US 2018/0002380 A1 | 2018 | Synthetic | NA | In vitro | A549, HT1376, MDA-MB-231, HeLa cells, BEAS-2B | Age related autophagy-related diseases | Effective in detecting and imaging autophagy in vitro and in vivo |
| AAPeptide035 | AtgPep-4 | US 2018/0002380 A1 | 2018 | Synthetic | NA | In vitro | A549, HT1376, MDA-MB-231, HeLa cells, BEAS-2B | Age related autophagy-related diseases | Effective in detecting and imaging autophagy in vitro and in vivo |
| AAPeptide036 | CG-Noverin | US 2019/0040100 A1, US 10487113 B2, US 10047125 B2 | 2018,2019 | Natural | Human | In vitro | Human periodontal ligament fibroblast cells,Human Dermal Fibroblast Cells (NIH3T3) | Skin aging | Wrinkle reduction, Skin and wound regeneration, elasticity improvement, Inhibites collagen degradation and melanosome transfer |
| AAPeptide037 | AtgPep-2 | US 2018/0002380 A1 | 2018 | Synthetic | NA | In vitro | A549, HT1376, MDA-MB-231, HeLa cells, BEAS-2B | Age related autophagy-related diseases | Effective in detecting and imaging autophagy in vitro and in vivo |
| AAPeptide038 | CG-Renuin | US 2019/0040100 A1, US 10487113 B2, US 10047125 B2 | 2018,2019 | Natural | Human | In vitro | Human Dermal Fibroblast Cells (NIH3T3) | Skin aging | Wrinkle reduction, Skin and wound regeneration, elasticity improvement, Inhibites collagen degradation and melanosome transfer |
| AAPeptide039 | MyD88 inhibitor | EP 3366302 A1 | 2018 | Synthetic | NA | In vitro, In vivo, Ex vivo | Primary mouse RPE cells, HeLa cells, THP-1 cells, Wild-type C57BL/6J mice | Age-related macular degeneration | Cell protection |
| AAPeptide040 | Transient Receptor Potential Vanilloid 3 (TRPV3) agonist | US 2018/0085296 A1 | 2018 | Natural | NA | In vitro | HEK-293 cells, Human keratinocyte cell line (HaCaT) | Skin aging | Promotes tissue repair, Removes the presence of dead skin and/or increasing the rate of new skin formation |