AagingBase: Database of anti-aging peptides
A manually curated comprehensive database for anti-aging peptidesThe Literature info page of AAPeptide gives experimental informations of anti-aging peptides of AagingBase that were collected from scholarly articles and patents. Users can find the data in a filterable and sortable table. To obtain further details, refer to the Help page.
| AAP_ID | Reported name | ID | Year | Origin | Source | Experiment type | Cell lines/Animal model | Condition addressed | Bioactivity |
|---|---|---|---|---|---|---|---|---|---|
| AAPeptide221 | 2-3 | US 10945940 B2 | 2021 | Natural | Bird or mammal | In vitro | Human dermal fibroblast | Skin aging | Improves skin aging or skin wrinkles |
| AAPeptide222 | NA | US 11103436 B2 | 2021 | Synthetic | NA | In vitro | Mouse fibroblast NIH3T3 cell line, Human keratinocyte (HaCaT) cell line | Skin aging, Anti-aging component of functional food | Treats skin disease, Improves skin condition |
| AAPeptide223 | Peptides of IGFBP-2 | US 10947285 B2 | 2021 | Synthetic | NA | In vitro | MC-3T3 E1 clone 4 (CL4) osteoblast cells | Skeletal aging | Preventing and/or treating bone disorders |
| AAPeptide224 | NA | US 11103436 B2 | 2021 | Synthetic | NA | In vitro | Mouse fibroblast NIH3T3 cell line, Human keratinocyte HaCaT cell line | Skin aging, Anti-aging component of functional food | Treats skin disease, Improves skin condition |
| AAPeptide225 | NA | US 2021/0009637 A1 | 2021 | Natural | Jelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa). | In vitro | Human fibroblast cell line (CCD-966SK) | Skin aging | Inhibits collagen breakdown, Increases the production of collagen, elastin and/or hyaluronic acid, regarding aging, Improves skin and inhibits inflammation |
| AAPeptide226 | NA | US 2021/0009637 A1 | 2021 | Natural | Jelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa). | In vitro | Human fibroblast cell line (CCD-966SK) | Skin aging | Inhibits collagen breakdown, Increases the production of collagen, elastin and/or hyaluronic acid, regarding aging, Improves skin and inhibits inflammation |
| AAPeptide227 | NA | US 2021/0009637 A1 | 2021 | Natural | Jelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa). | In vitro | Human fibroblast cell line (CCD-966SK) | Skin aging | Inhibits collagen breakdown, Increases the production of collagen, elastin and/or hyaluronic acid, regarding aging, Improves skin and inhibits inflammation |
| AAPeptide228 | NA | US 2021/0009637 A1 | 2021 | Natural | Jelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa). | In vitro | Human fibroblast cell line (CCD-966SK) | Skin aging | Inhibits collagen breakdown, Increases the production of collagen, elastin and/or hyaluronic acid, regarding aging, Improves skin and inhibits inflammation |
| AAPeptide229 | NA | US 2021/0009637 A1 | 2021 | Natural | Jelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa). | In vitro | Human fibroblast cell line (CCD-966SK) | Skin aging | Inhibits collagen breakdown, Increases the production of collagen, elastin and/or hyaluronic acid, regarding aging, Improves skin and inhibits inflammation |
| AAPeptide230 | DKY21 | US 2021/0040152 A1 | 2021 | Natural | Human | In vitro, In vivo | Human cervical carcinoma cells Hela, 3-6 month old wild mice | Skin aging | Inhibits the telomere DNA damage caused by irradiation of X rays |
| AAPeptide231 | Gal2–Pep | 35479554 | 2021 | Synthetic | NA | In vitro | HaCaT cells, CCD-1064Sk (Normal human skin fibroblast) cells | Skin aging | Eliminates free radicals within the skin, Increases the expression of PGC-1α, which regulates mitochondrial synthesis |
| AAPeptide232 | NA | US 11103436 B2 | 2021 | Synthetic | NA | In vitro | Mouse fibroblast NIH3T3 cell line, Human keratinocyte HaCaT cell line | Skin aging, Anti-aging component of functional food | Treats skin disease, Improves skin condition |
| AAPeptide233 | NA | US 2021/0009637 A1 | 2021 | Natural | Jelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa). | In vitro | Human fibroblast cell line (CCD-966SK) | Skin aging | Inhibits the telomere DNA damage caused by irradiation of X rays |
| AAPeptide234 | NA | US 10905734 B2 | 2021 | Synthetic | NA | In vitro | Human Dermal Fibroblasts (HDF) | Skin aging, Anti-aging component of functional food | Inhibits skin aging, Treats disease or condition characterised by damaged epithelial cells or tissue, Maintains gut health and muscle health in a mammal |
| AAPeptide235 | NA | US 2021/0009637 A1 | 2021 | Natural | Jelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa). | In vitro | Human fibroblast cell line (CCD-966SK) | Skin aging | Decreases collagen breakdown, Increases production of collagen, elastin and/or hyaluronic acid, Retards aging, Improves skin and inhibits inflammation |
| AAPeptide236 | Water-soluble royal jelly protein (WSRJP) | NA | 2021 | Natural | Apis mellifera | In vitro | Human monocytic leukemia cell line U3-1 | Anti-aging ingredient of functional food | Protects cultured human cells against oxidative stress-induced cell death |
| AAPeptide237 | Pine nut protein hydrolysate (PNPH)-P7 | 33289247 | 2021 | Natural | Pinus yunnanensis Franch | In vitro, In vivo | HepG2, SPF Kunming mice | D-Galactose induced aging | Have potential application prospects in the field of natural antioxidants and anti-aging functional foods |
| AAPeptide238 | ATF3 Protein-Binding Peptide | US 2021/0355164 A1 | 2021 | Synthetic | NA | In vitro, In vivo | HepG2 cells, C57BL/6J mice | Skin aging | Addresses oxidative stress, skin diseases, skin aging, damage caused by UV irradiation |
| AAPeptide239 | Pine nut protein hydrolysate (PNPH)-P3 | 33289247 | 2021 | Natural | Pinus yunnanensis Franch | In vitro, In vivo | HepG2 , SPF Kunming mice | D-Galactose induced aging | Have potential application prospects in the field of natural antioxidants and anti-aging functional foods |
| AAPeptide240 | Angiotensin(Ang)-(1-7) | 33247425 | 2021 | Natural | Human | In vivo | C57Bl/6 mice | Ischemic vascular repair | Restores reparative functions in HSPCs and ischemic vascular repair |