AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide231

The Peptide Card page for AAPeptide231 gives textual and graphical visualizations of the properties of AAPeptide231. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide231.
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AAP ID	AAPeptide231
Peptide name	Gal2–Pep
PubMed/Patent ID	35479554
Origin	Synthetic
Source of Origin	NA
Condition addressed	Skin aging
Experiment type	In vitro
Cell lines/Animal model	HaCaT cells, CCD-1064Sk (Normal human skin fibroblast) cells
Intervention	Cells were treated with the peptide
Experiment methods	qRT-PCR, CCK-8 Cell viability assay, Antioxidant activity, DPPH assay, ROS scavenging assay, Mitochondrial membrane potential assay, Elastase inhibitory activity assay
Patient group	NA
Markers used	NA
Mechanism of action	Eliminates free radicals within the skin, Increases the expression of PGC-1α, which regulates mitochondrial synthesis

Molecular weight	740.845
Peptide length	7
Instability index	36.086
Aromaticity	0.000
Aliphaticity	0.429
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	8.750
Composition of positively charged residues	0.143
Composition of negatively charged residues	0.000
Composition of neutral charged residues	0.857
Composition of residues polar residues	0.429
Composition of residues non-polar residues	0.429
Composition of residues having cyclic side chain	0.429
Composition of acidic residues	0.000
Composition of basic residues	0.143
Composition of residues having cyclic side chain	0.429
Composition of hydroxylic residues	0.429
Composition of residue in buried solvent accessibility	0.000
Composition of residue in exposed solvent accessibility	0.571
Composition of residue in intermediate solvent accessibility	0.857

AAPeptide231 :

KTPPTTP

Amino acid data

ProtScale

Disclaimer: Hydropathy plot is not available for AAPeptide231 as the peptide length is less than 9 amino acid residues

Atomic information

3D Structure

Structural Representation of AAPeptide231

Amino acid data

Secondary structure fraction