AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

2. AAPeptide literature info page

AAPeptide web page has modules in the dropdown. This page shows the literature info collected from research articles and patents.

Column headers

AAP ID: It is the unique ID given to each unique peptide of AagingBase
Reported Name: It is the name of the peptide mentioned in the research articles or patents.
ID: It refers to the PubMed or the patent ID in which the peptide is reported.
Year: It is the year of publication.
Origin: It says if a peptide is natural/synthetic in nature.
Experiment type: It refers to the type of experiment that is- in vitro, in vivo -to validate the anti-aging property of the peptide.
Cell lines/Animal model: It refers to the model system that is the name of the cell lines or animal model used for the experiments conducted to validate the anti-aging property of the peptide.
Condition Addressed: This refers to the specific age-related condition or disease that was targeted in the experiment involving the use of the peptide. It can range from addressing wrinkles formation due to skin aging.
Bioactivity: Action mechanism of the peptide.

3. AAPeptide physicochemical info page

The page shows 26 calculated physicochemical information of the peptides of AagingBase in a sortable column

4. AAPeptide structural info page

The page shows the calculated secondary structure fractions of the peptides of AagingBase in a sortable column. It has amino acids V, I, Y, F, W and L in the helix fraction; N, P, G and S in the turn fraction and E, M, A and L in the sheet fraction

5. AAPeptide motif info page

The page has the motifs discovered from AAPeptides.

6. AAPeptide advanced search page

The page allows the user to do a key word search on the fields of AAP ID, PubMed ID, Patent ID, Condition addressed, Year and Sequence.

7. Advanced search result page

This is an example result page for Adavanced Search done using the keyword "AAPeptide001".

Result page:
The page returns AAP ID, Peptide length, Sequence, In vivo Stability, Experiment type, Model, Intervention, Method, Mechanism of action and PubMed/Patent ID.
Peptide length and Sequence: It is the peptide length and sequence of the peptide associated with the query.
In vivo stability: It states if the peptide associated with the query is stable or unstable in a test tube condition.
Experiment type: It states the type of experiment that is in vitro or in vivo conducted to ensure the anti-aging property of the peptide.
Model: The model system used to conduct the experiment.
Intervention: It states the method in which the peptide was administrated to the model system for anti-aging experiments.
Method: It is the experimental methods conducted to check for the anti-aging property of the peptide.
Mechanism of action: It is the effect of the peptide on the model system after the experimental methods.
PubMed ID/Patent ID: It is the PubMed ID or the patent ID related with the peptide associated with the query.

8. BLASTP similarity search page

The page allows the user to do a BLAST-P similarity search against the peptides of AagingBase.

9. BLASTP similarity search result page

The page shows the result of the the BLASTP similarity search of the example sequence against sequences of AagingBase.

10. Smith-Waterman similarity page

11. Smith-Waterman similarity search result page

The page shows the result of the the Smith-Waterman similarity search of the example sequence against sequences of AagingBase.

12. Download page

The page allows the user to download the datatasets of AagingBase.