AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide230

The Peptide Card page for AAPeptide230 gives textual and graphical visualizations of the properties of AAPeptide230. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide230.
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AAP ID	AAPeptide230
Peptide name	DKY21
PubMed/Patent ID	US 2021/0040152 A1
Origin	Natural
Source of Origin	Human
Condition addressed	Skin aging
Experiment type	In vitro, In vivo
Cell lines/Animal model	Human cervical carcinoma cells Hela, 3-6 month old wild mice
Intervention	Cells were treated with the peptide, Topical application of the peptide on the mice after X-ray irradiation
Experiment methods	PCR, Immunofluorescence assay, FISH
Patient group	NA
Markers used	α-SMA
Mechanism of action	Inhibits the telomere DNA damage caused by irradiation of X rays

Molecular weight	2619.904
Peptide length	21
Instability index	145.495
Aromaticity	0.048
Aliphaticity	0.143
Reduced molecular extinction coeffecient	1490
Oxidized molecular extinction coeffecient	1490
Isoelectric point	11.888
Composition of positively charged residues	0.476
Composition of negatively charged residues	0.095
Composition of neutral charged residues	0.429
Composition of residues polar residues	0.238
Composition of residues non-polar residues	0.143
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.095
Composition of basic residues	0.476
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.143
Composition of residue in buried solvent accessibility	0.143
Composition of residue in exposed solvent accessibility	0.333
Composition of residue in intermediate solvent accessibility	0.190

AAPeptide230 :

KTEETGNRSGRRRQRRKKRGY

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide230

Amino acid data

Secondary structure fraction