AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide022

The Peptide Card page for AAPeptide022 gives textual and graphical visualizations of the properties of AAPeptide022. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide022.
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AAP ID	AAPeptide022
Peptide name	Pep-WH-3
PubMed/Patent ID	US 2018/0134749 A3,EP 3305802 A1
Origin	Synthetic
Source of Origin	NA
Condition addressed	Skin aging
Experiment type	In vitro
Cell lines/Animal model	THP-1, HepG2
Intervention	Treated with the peptide(in the medium)
Experiment methods	HPLC, Western blot, ELISA
Patient group	NA
Markers used	pSmad2/3 , Smad2/3 , GAPDH
Mechanism of action	Anti-inflammation, Anti-fibrosis, Wound healing, Anti-cancer treatment, Improves skin condition

Molecular weight	949.108
Peptide length	8
Instability index	80.975
Aromaticity	0.125
Aliphaticity	0.375
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	12.000
Composition of positively charged residues	0.250
Composition of negatively charged residues	0.000
Composition of neutral charged residues	0.750
Composition of residues polar residues	0.250
Composition of residues non-polar residues	0.500
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.000
Composition of basic residues	0.250
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.250
Composition of residue in buried solvent accessibility	0.500
Composition of residue in exposed solvent accessibility	0.000
Composition of residue in intermediate solvent accessibility	0.250

AAPeptide022 :

ALSSRLRF

Amino acid data

ProtScale

Disclaimer: Hydropathy plot is not available for AAPeptide022 as the peptide length is less than 9 amino acid residues

Atomic information

3D Structure

Structural Representation of AAPeptide022

Amino acid data

Secondary structure fraction