AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide276

The Peptide Card page for AAPeptide276 gives textual and graphical visualizations of the properties of AAPeptide276. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide276.
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AAP ID	AAPeptide276
Peptide name	Repair peptide 2
PubMed/Patent ID	US 11260101 B2
Origin	Synthetic
Source of Origin	NA
Condition addressed	Wound repair of the skin tissue and nerve injury repair
Experiment type	In vitro, In vivo
Cell lines/Animal model	Mouse fibroblasts balb/c 3T3, Human umbilical vein endothelial cells (HUVEC), Chick embryo chorioallantoic membranes, Animal models of mice and rats
Intervention	Cells were treated with the peptide, Peptide was administrated as drops into the wounds generated on in vivo model
Experiment methods	Isothermal totration calorimetry (ITC) affinity detection, CCK-8 Cell proliferation assay, Detection of the Angiogenesis in the Chick Embryo Chorioallantoic Membrane, Detection of the Wound Healing in Rat Skin, Mechanical pain stimulation test, Immunofluorescence
Patient group	NA
Markers used	NF200 (marker protein of nerve fibers), Laminin (marker protein of peripheral nerve fibers)
Mechanism of action	A good wound repair and cell regeneration and proliferation product which can replace the recombinant bFGF

Molecular weight	1365.706
Peptide length	13
Instability index	-15.254
Aromaticity	0.000
Aliphaticity	0.615
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	10.478
Composition of positively charged residues	0.308
Composition of negatively charged residues	0.000
Composition of neutral charged residues	0.692
Composition of residues polar residues	0.000
Composition of residues non-polar residues	0.615
Composition of residues having cyclic side chain	0.077
Composition of acidic residues	0.000
Composition of basic residues	0.308
Composition of residues having cyclic side chain	0.077
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.538
Composition of residue in exposed solvent accessibility	0.462
Composition of residue in intermediate solvent accessibility	0.077

AAPeptide276 :

KVKVGPANVKVKV

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide276

Amino acid data

Secondary structure fraction