AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide276


The Peptide Card page for AAPeptide276 gives textual and graphical visualizations of the properties of AAPeptide276. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide276.
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AAP IDAAPeptide276
Peptide nameRepair peptide 2
PubMed/Patent IDUS 11260101 B2
OriginSynthetic
Source of OriginNA
Condition addressedWound repair of the skin tissue and nerve injury repair
Experiment typeIn vitro, In vivo
Cell lines/Animal modelMouse fibroblasts balb/c 3T3, Human umbilical vein endothelial cells (HUVEC), Chick embryo chorioallantoic membranes, Animal models of mice and rats
InterventionCells were treated with the peptide, Peptide was administrated as drops into the wounds generated on in vivo model
Experiment methodsIsothermal totration calorimetry (ITC) affinity detection, CCK-8 Cell proliferation assay, Detection of the Angiogenesis in the Chick Embryo Chorioallantoic Membrane, Detection of the Wound Healing in Rat Skin, Mechanical pain stimulation test, Immunofluorescence
Patient groupNA
Markers usedNF200 (marker protein of nerve fibers), Laminin (marker protein of peripheral nerve fibers)
Mechanism of actionA good wound repair and cell regeneration and proliferation product which can replace the recombinant bFGF
Molecular weight1365.706
Peptide length13
Instability index-15.254
Aromaticity0.000
Aliphaticity0.615
Reduced molecular extinction coeffecient0
Oxidized molecular extinction coeffecient0
Isoelectric point10.478
Composition of positively charged residues0.308
Composition of negatively charged residues0.000
Composition of neutral charged residues0.692
Composition of residues polar residues0.000
Composition of residues non-polar residues0.615
Composition of residues having cyclic side chain0.077
Composition of acidic residues0.000
Composition of basic residues0.308
Composition of residues having cyclic side chain0.077
Composition of hydroxylic residues0.000
Composition of residue in buried solvent accessibility0.538
Composition of residue in exposed solvent accessibility0.462
Composition of residue in intermediate solvent accessibility0.077

AAPeptide276 :
KVKVGPANVKVKV

Amino acid data
ProtScale
Atomic information


3D Structure

Structural Representation of AAPeptide276

Amino acid data
Secondary structure fraction