AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide267

The Peptide Card page for AAPeptide267 gives textual and graphical visualizations of the properties of AAPeptide267. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide267.
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AAP ID	AAPeptide267
Peptide name	Repair peptide 4
PubMed/Patent ID	US 11260101 B2
Origin	Synthetic
Source of Origin	NA
Condition addressed	Wound repair of the skin tissue and nerve injury repair
Experiment type	In vitro, In vivo
Cell lines/Animal model	Mouse fibroblasts balb/c 3T3, Human umbilical vein endothelial cells (HUVEC), Chick embryo chorioallantoic membranes, Animal models of mice and rats
Intervention	Cells were treated with the peptide, Peptide was administrated as drops into the wounds generated on in vivo model
Experiment methods	Isothermal totration calorimetry (ITC) affinity detection, CCK-8 Cell proliferation assay, Detection of the Angiogenesis in the Chick Embryo Chorioallantoic Membrane, Detection of the Wound Healing in Rat Skin, Mechanical pain stimulation test, Immunofluorescence
Patient group	NA
Markers used	NF200 (marker protein of nerve fibers), Laminin (marker protein of peripheral nerve fibers)
Mechanism of action	A good wound repair and cell regeneration and proliferation product which can replace the recombinant bFGF

Molecular weight	892.997
Peptide length	9
Instability index	30.289
Aromaticity	0.000
Aliphaticity	0.444
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	125
Isoelectric point	4.050
Composition of positively charged residues	0.000
Composition of negatively charged residues	0.111
Composition of neutral charged residues	0.889
Composition of residues polar residues	0.333
Composition of residues non-polar residues	0.444
Composition of residues having cyclic side chain	0.111
Composition of acidic residues	0.111
Composition of basic residues	0.000
Composition of residues having cyclic side chain	0.111
Composition of hydroxylic residues	0.111
Composition of residue in buried solvent accessibility	0.556
Composition of residue in exposed solvent accessibility	0.333
Composition of residue in intermediate solvent accessibility	0.222

AAPeptide267 :

CGPANVETC

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide267

Amino acid data

Secondary structure fraction