AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide264

The Peptide Card page for AAPeptide264 gives textual and graphical visualizations of the properties of AAPeptide264. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide264.
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AAP IDAAPeptide264
Peptide nameNA
PubMed/Patent IDUS 2021/0017240 A1
OriginNatural
Source of OriginSunflower seed
Condition addressedOxidative stress, Anti-aging component of functional food
Experiment typeIn vitro
Cell lines/Animal modelHuman A549 cells
InterventionCells were treated with the peptide
Experiment methodsNFκB-luciferase Reporter Gene Assay, Co-Stimulatory Molecule Expression (Cluster of Differentiation (CD)) Assay, Nuclear Factor (Erythroid-Derived 2)-like 2 (NRF-2) Assay, Quinone Reductase (QR) Assay, DPPH Assay, Hydroxyl Radical Scavenging Activity Assay, Nitric Oxide (NO) Production Assay, ACE Inhibition Assay, Renin Inhibition Assay
Patient groupNA
Markers usedCD14, CD86
Mechanism of actionReduces blood pressure, inflammation, Enhances immune activity, Decreases reactive oxidants, Induces vasodilation, Improves, Reduces the activity of angiotensin converting enzyme (ACE), Activates NAD(P)H:quinone reductase (QR), Reduces expression of mRNA for renin, Induces a drug-metabolizing enzyme, Activates nuclear factor erythroid 2 (NFE2)-related factor 2 (Nrf2)
Molecular weight524.608
Peptide length4
Instability index55.650
Aromaticity0.500
Aliphaticity0.500
Reduced molecular extinction coeffecient1490
Oxidized molecular extinction coeffecient1490
Isoelectric point5.524
Composition of positively charged residues0.000
Composition of negatively charged residues0.000
Composition of neutral charged residues1.000
Composition of residues polar residues0.250
Composition of residues non-polar residues0.750
Composition of residues having cyclic side chain0.250
Composition of acidic residues0.000
Composition of basic residues0.000
Composition of residues having cyclic side chain0.250
Composition of hydroxylic residues0.000
Composition of residue in buried solvent accessibility0.500
Composition of residue in exposed solvent accessibility0.250
Composition of residue in intermediate solvent accessibility0.500

AAPeptide264 :
YFVP

Amino acid data
ProtScale


Disclaimer: Hydropathy plot is not available for AAPeptide264 as the peptide length is less than 9 amino acid residues

Atomic information


3D Structure

Structural Representation of AAPeptide264

Amino acid data
Secondary structure fraction