AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide261

The Peptide Card page for AAPeptide261 gives textual and graphical visualizations of the properties of AAPeptide261. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide261.
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AAP ID	AAPeptide261
Peptide name	Tmem100 mutant polypeptide
PubMed/Patent ID	US 11066455 B2
Origin	Natural
Source of Origin	Mus musculus
Condition addressed	Pain occuring with aging
Experiment type	In vivo
Cell lines/Animal model	Mice
Intervention	Tmem100 GFP Knock-in/Knockout Mouse Line, Rat L5 SNL
Experiment methods	Western Blot, Co-Immunoprecipitation (Co-IP), GST Pull-Down, Hot Plate Methods, Tail Immersion Test, Von Frey Methods, Cold Plate Test, Calcium imaging assays, Electrophysiology, Immunofluorescent Staining
Patient group	NA
Markers used	NA
Mechanism of action	Enhances TRPA1 Activity

Molecular weight	3386.886
Peptide length	28
Instability index	61.900
Aromaticity	0.071
Aliphaticity	0.286
Reduced molecular extinction coeffecient	5500
Oxidized molecular extinction coeffecient	5500
Isoelectric point	11.009
Composition of positively charged residues	0.214
Composition of negatively charged residues	0.036
Composition of neutral charged residues	0.750
Composition of residues polar residues	0.321
Composition of residues non-polar residues	0.357
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.036
Composition of basic residues	0.214
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.071
Composition of residue in buried solvent accessibility	0.393
Composition of residue in exposed solvent accessibility	0.429
Composition of residue in intermediate solvent accessibility	0.071

AAPeptide261 :

WKVRQRNKKVQQQESQTALVVNQRCLFA

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide261

Amino acid data

Secondary structure fraction