AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide260

The Peptide Card page for AAPeptide260 gives textual and graphical visualizations of the properties of AAPeptide260. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide260.
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AAP ID	AAPeptide260
Peptide name	Tmem100 mutant polypeptide
PubMed/Patent ID	US 11066455 B2
Origin	Natural
Source of Origin	Mus musculus
Condition addressed	Pain occuring with aging
Experiment type	In vivo
Cell lines/Animal model	Mice
Intervention	Tmem100 GFP Knock-in/Knockout Mouse Line, Rat L5 SNL
Experiment methods	Western Blot, Co-Immunoprecipitation (Co-IP), GST Pull-Down, Hot Plate Methods, Tail Immersion Test, Von Frey Methods, Cold Plate Test, Calcium imaging assays, Electrophysiology, Immunofluorescent Staining
Patient group	NA
Markers used	NA
Mechanism of action	Enhances TRPA1 Activity

Molecular weight	2242.497
Peptide length	18
Instability index	84.222
Aromaticity	0.056
Aliphaticity	0.167
Reduced molecular extinction coeffecient	5500
Oxidized molecular extinction coeffecient	5500
Isoelectric point	11.097
Composition of positively charged residues	0.278
Composition of negatively charged residues	0.056
Composition of neutral charged residues	0.667
Composition of residues polar residues	0.389
Composition of residues non-polar residues	0.222
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.056
Composition of basic residues	0.278
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.111
Composition of residue in buried solvent accessibility	0.222
Composition of residue in exposed solvent accessibility	0.556
Composition of residue in intermediate solvent accessibility	0.111

AAPeptide260 :

WKVRQRNKKVQQQESQTA

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide260

Amino acid data

Secondary structure fraction