AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide256

The Peptide Card page for AAPeptide256 gives textual and graphical visualizations of the properties of AAPeptide256. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide256.
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AAP ID	AAPeptide256
Peptide name	Hexapeptide-12
PubMed/Patent ID	US 11052032 B2
Origin	Synthetic
Source of Origin	NA
Condition addressed	Aging associated skin laxity
Experiment type	In vitro, In vivo, Randomized clinical trial
Cell lines/Animal model	Dermal fibroblasts, 3T3-L1 adipocytes
Intervention	Cells were traeted with the peptide, Topical application of the formulation on a patient undergoing Coolsculpting
Experiment methods	Gene expression profiling, Macrophage Clustering
Patient group	Women between 25 and 65 years of age to assess the efficacy of the regenerating body complex (RBC)
Markers used	NA
Mechanism of action	Improves skin laxity, texture, or crepiness or body contouring

Molecular weight	498.573
Peptide length	6
Instability index	26.283
Aromaticity	0.000
Aliphaticity	1.000
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	5.495
Composition of positively charged residues	0.000
Composition of negatively charged residues	0.000
Composition of neutral charged residues	1.000
Composition of residues polar residues	0.000
Composition of residues non-polar residues	1.000
Composition of residues having cyclic side chain	0.167
Composition of acidic residues	0.000
Composition of basic residues	0.000
Composition of residues having cyclic side chain	0.167
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.833
Composition of residue in exposed solvent accessibility	0.167
Composition of residue in intermediate solvent accessibility	0.167

AAPeptide256 :

VGVAPG

Amino acid data

ProtScale

Disclaimer: Hydropathy plot is not available for AAPeptide256 as the peptide length is less than 9 amino acid residues

Atomic information

3D Structure

Structural Representation of AAPeptide256

Amino acid data

Secondary structure fraction