AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide253

The Peptide Card page for AAPeptide253 gives textual and graphical visualizations of the properties of AAPeptide253. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide253.
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AAP ID	AAPeptide253
Peptide name	NA
PubMed/Patent ID	US 2021/0017240 A1
Origin	Natural
Source of Origin	Sunflower seed
Condition addressed	Oxidative stress, Anti aging component of functional food
Experiment type	In vitro
Cell lines/Animal model	Human A549 cells
Intervention	Cells were treated with the peptide
Experiment methods	NFκB-luciferase Reporter Gene Assay, Co-Stimulatory Molecule Expression (Cluster of Differentiation (CD)) Assay, Nuclear Factor (Erythroid-Derived 2)-like 2 (NRF-2) Assay, Quinone Reductase (QR) Assay, DPPH Assay, Hydroxyl Radical Scavenging Activity Assay, Nitric Oxide (NO) Production Assay, ACE Inhibition Assay, Renin Inhibition Assay
Patient group	NA
Markers used	CD14, CD89
Mechanism of action	Reduces blood pressure, inflammation, Enhances immune activity, Decreases reactive oxidants, Induces vasodilation, Improves, Reduces the activity of angiotensin converting enzyme (ACE), Activates NAD(P)H:quinone reductase (QR), Reduces expression of mRNA for renin, Induces a drug-metabolizing enzyme, Activates nuclear factor erythroid 2 (NFE2)-related factor 2 (Nrf2)

Molecular weight	986.977
Peptide length	9
Instability index	25.133
Aromaticity	0.222
Aliphaticity	0.222
Reduced molecular extinction coeffecient	6990
Oxidized molecular extinction coeffecient	6990
Isoelectric point	4.050
Composition of positively charged residues	0.000
Composition of negatively charged residues	0.111
Composition of neutral charged residues	0.889
Composition of residues polar residues	0.556
Composition of residues non-polar residues	0.333
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.111
Composition of basic residues	0.000
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.444
Composition of residue in buried solvent accessibility	0.333
Composition of residue in exposed solvent accessibility	0.111
Composition of residue in intermediate solvent accessibility	0.556

AAPeptide253 :

TGSYTEGWS

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide253

Amino acid data

Secondary structure fraction