AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide249

The Peptide Card page for AAPeptide249 gives textual and graphical visualizations of the properties of AAPeptide249. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide249.
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AAP IDAAPeptide249
Peptide nameNA
PubMed/Patent IDUS 2021/0009637 A1
OriginNatural
Source of OriginJelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa).
Condition addressedSkin aging
Experiment typeIn vitro
Cell lines/Animal modelHuman fibroblast cell line (CCD-966SK)
InterventionCells were treated with the peptide
Experiment methodsAssay in Increasing Expression of Genes
Patient groupNA
Markers usedNADSYN,Atg1, Ubl-5,FOXO,MRPS5, CCT2 and/or CCT8(Anti-aging gene), TERC(Telomerase genes), ERCC1,UNG, MSH6, XRCCS and/or MSH6(DNA repair genes), SMPD1,ELG-F and GBA(Moisture-retention related genes), collagen I gene, collagen IV gene, elastin genes, TIMP1, MMP-1
Mechanism of actionDecreases collagen breakdown, Increases the production of collagen, elastin and/or hyaluronic acid, Retards aging, Improves skin and inhibits inflammation
Molecular weight506.620
Peptide length4
Instability index7.500
Aromaticity0.000
Aliphaticity0.000
Reduced molecular extinction coeffecient0
Oxidized molecular extinction coeffecient0
Isoelectric point9.508
Composition of positively charged residues0.500
Composition of negatively charged residues0.000
Composition of neutral charged residues0.500
Composition of residues polar residues0.500
Composition of residues non-polar residues0.000
Composition of residues having cyclic side chain0.000
Composition of acidic residues0.000
Composition of basic residues0.500
Composition of residues having cyclic side chain0.000
Composition of hydroxylic residues0.250
Composition of residue in buried solvent accessibility0.250
Composition of residue in exposed solvent accessibility0.250
Composition of residue in intermediate solvent accessibility0.250

AAPeptide249 :
RTCK

Amino acid data
ProtScale


Disclaimer: Hydropathy plot is not available for AAPeptide249 as the peptide length is less than 9 amino acid residues

Atomic information


3D Structure

Structural Representation of AAPeptide249

Amino acid data
Secondary structure fraction