AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide247

The Peptide Card page for AAPeptide247 gives textual and graphical visualizations of the properties of AAPeptide247. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide247.
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AAP IDAAPeptide247
Peptide nameNA
PubMed/Patent IDUS 2021/0009637 A1
OriginNatural
Source of OriginJelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa).
Condition addressedSkin aging
Experiment typeIn vitro
Cell lines/Animal modelHuman fibroblast cell line (CCD-966SK)
InterventionCells were treated with the peptide
Experiment methodsAssay in Increasing Expression of Genes
Patient groupNA
Markers usedNADSYN,Atg1, Ubl-5,FOXO,MRPS5, CCT2 and/or CCT8(Anti-aging gene), TERC(Telomerase genes), ERCC1,UNG, MSH6, XRCCS and/or MSH6(DNA repair genes), SMPD1,ELG-F and GBA(Moisture-retention related genes), collagen I gene, collagen IV gene, elastin genes, TIMP1, MMP-1
Mechanism of actionDecreases collagen breakdown, Increases the production of collagen, elastin and/or hyaluronic acid, Retards aging, Improves skin and inhibits inflammation
Molecular weight1045.278
Peptide length8
Instability index-21.900
Aromaticity0.125
Aliphaticity0.375
Reduced molecular extinction coeffecient1490
Oxidized molecular extinction coeffecient1490
Isoelectric point10.290
Composition of positively charged residues0.375
Composition of negatively charged residues0.000
Composition of neutral charged residues0.625
Composition of residues polar residues0.250
Composition of residues non-polar residues0.375
Composition of residues having cyclic side chain0.125
Composition of acidic residues0.000
Composition of basic residues0.375
Composition of residues having cyclic side chain0.125
Composition of hydroxylic residues0.000
Composition of residue in buried solvent accessibility0.250
Composition of residue in exposed solvent accessibility0.500
Composition of residue in intermediate solvent accessibility0.250

AAPeptide247 :
QRIKYIKP

Amino acid data
ProtScale


Disclaimer: Hydropathy plot is not available for AAPeptide247 as the peptide length is less than 9 amino acid residues

Atomic information


3D Structure

Structural Representation of AAPeptide247

Amino acid data
Secondary structure fraction