AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide245

The Peptide Card page for AAPeptide245 gives textual and graphical visualizations of the properties of AAPeptide245. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide245.
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AAP IDAAPeptide245
Peptide nameNA
PubMed/Patent IDUS 11155579 B2,US 2021/0009637 A1
OriginNatural
Source of OriginJelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa).
Condition addressedSkin aging
Experiment typeIn vitro
Cell lines/Animal modelHuman fibroblast cell line (CCD-966SK)
InterventionCells were treated with the peptide
Experiment methodsAssay in Increasing Expression of Genes
Patient groupNA
Markers usedAtg1, Ubl-5 and FOXO (anti-aging genes), TERC (telomerase genes), ERCC1 (DNA repair genes), ELG-F and GBA (moisture-retention related genes), collagen I gene, collagen IV gene, elastin genes and TIMP1,NADSYN,Atg1, Ubl-5,FOXO,MRPS5, CCT2 and/or CCT8(Anti-aging gene), TERC(Telomerase genes), ERCC1,UNG, MSH6, XRCCS and/or MSH6(DNA repair genes), SMPD1,ELG-F and GBA(Moisture-retention related genes), collagen I gene, collagen IV gene, elastin genes, TIMP1, MMP-1
Mechanism of actionDecreases collagen breakdown, Increases the production of collagen, elastin and/or hyaluronic acid, Retards aging, Improves skin and inhibits inflammation
Molecular weight919.107
Peptide length7
Instability index136.971
Aromaticity0.000
Aliphaticity0.000
Reduced molecular extinction coeffecient0
Oxidized molecular extinction coeffecient0
Isoelectric point11.013
Composition of positively charged residues0.571
Composition of negatively charged residues0.000
Composition of neutral charged residues0.429
Composition of residues polar residues0.429
Composition of residues non-polar residues0.000
Composition of residues having cyclic side chain0.000
Composition of acidic residues0.000
Composition of basic residues0.571
Composition of residues having cyclic side chain0.000
Composition of hydroxylic residues0.143
Composition of residue in buried solvent accessibility0.143
Composition of residue in exposed solvent accessibility0.429
Composition of residue in intermediate solvent accessibility0.143

AAPeptide245 :
QKRRTCK

Amino acid data
ProtScale


Disclaimer: Hydropathy plot is not available for AAPeptide245 as the peptide length is less than 9 amino acid residues

Atomic information


3D Structure

Structural Representation of AAPeptide245

Amino acid data
Secondary structure fraction