AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide243

The Peptide Card page for AAPeptide243 gives textual and graphical visualizations of the properties of AAPeptide243. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide243.
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AAP IDAAPeptide243
Peptide nameNA
PubMed/Patent IDUS 2021/0009637 A1
OriginNatural
Source of OriginJelly fish (such as Chironex fleckeri), Sea anemone (such as Heteractis magnifica), Spider (such as Latrodectus mactans), Octopus (such as Hapalochlaena maculosa).
Condition addressedSkin aging
Experiment typeIn vitro
Cell lines/Animal modelHuman fibroblast cell line (CCD-966SK)
InterventionCells were treated with the peptide
Experiment methodsAssay in Increasing Expression of Genes
Patient groupNA
Markers usedNADSYN,Atg1, Ubl-5,FOXO,MRPS5, CCT2 and/or CCT8(Anti-aging gene), TERC(Telomerase genes), ERCC1,UNG, MSH6, XRCCS and/or MSH6(DNA repair genes), SMPD1,ELG-F and GBA(Moisture-retention related genes), collagen I gene, collagen IV gene, elastin genes, TIMP1, MMP-1
Mechanism of actionDecreases collagen breakdown, Increases production of collagen, elastin and/or hyaluronic acid, Retards aging, Improves skin and inhibits inflammation
Molecular weight609.761
Peptide length5
Instability index14.460
Aromaticity0.000
Aliphaticity0.600
Reduced molecular extinction coeffecient0
Oxidized molecular extinction coeffecient0
Isoelectric point11.006
Composition of positively charged residues0.400
Composition of negatively charged residues0.000
Composition of neutral charged residues0.600
Composition of residues polar residues0.000
Composition of residues non-polar residues0.600
Composition of residues having cyclic side chain0.400
Composition of acidic residues0.000
Composition of basic residues0.400
Composition of residues having cyclic side chain0.400
Composition of hydroxylic residues0.000
Composition of residue in buried solvent accessibility0.200
Composition of residue in exposed solvent accessibility0.600
Composition of residue in intermediate solvent accessibility0.400

AAPeptide243 :
PRPIK

Amino acid data
ProtScale


Disclaimer: Hydropathy plot is not available for AAPeptide243 as the peptide length is less than 9 amino acid residues

Atomic information


3D Structure

Structural Representation of AAPeptide243

Amino acid data
Secondary structure fraction