AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide241

The Peptide Card page for AAPeptide241 gives textual and graphical visualizations of the properties of AAPeptide241. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide241.
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AAP ID	AAPeptide241
Peptide name	NA
PubMed/Patent ID	US 2021/0017240 A1
Origin	Natural
Source of Origin	Sunflower seed
Condition addressed	Oxidative stress, Anti-aging component of functional food
Experiment type	In vitro
Cell lines/Animal model	Human A549 cells
Intervention	Cells were treated with the peptide
Experiment methods	NFκB-luciferase Reporter Gene Assay, Co-Stimulatory Molecule Expression (Cluster of Differentiation (CD)) Assay, Nuclear Factor (Erythroid-Derived 2)-like 2 (NRF-2) Assay, Quinone Reductase (QR) Assay, DPPH Assay, Hydroxyl Radical Scavenging Activity Assay, Nitric Oxide (NO) Production Assay, ACE Inhibition Assay, Renin Inhibition Assay
Patient group	NA
Markers used	CD14, CD88
Mechanism of action	Reduces blood pressure and inflammation, Enhances immune activity, Decreases reactive oxidants, Induces vasodilation, Inhibits the activity of angiotensin converting enzyme (ACE), Activates NAD(P)H:quinone reductase (QR) in the subject, Activates nuclear factor erythroid 2 (NFE2)-related factor 2 (Nrf2)

Molecular weight	588.719
Peptide length	5
Instability index	-12.740
Aromaticity	0.200
Aliphaticity	0.600
Reduced molecular extinction coeffecient	5500
Oxidized molecular extinction coeffecient	5500
Isoelectric point	5.275
Composition of positively charged residues	0.000
Composition of negatively charged residues	0.000
Composition of neutral charged residues	1.000
Composition of residues polar residues	0.000
Composition of residues non-polar residues	1.000
Composition of residues having cyclic side chain	0.200
Composition of acidic residues	0.000
Composition of basic residues	0.000
Composition of residues having cyclic side chain	0.200
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.600
Composition of residue in exposed solvent accessibility	0.200
Composition of residue in intermediate solvent accessibility	0.400

AAPeptide241 :

MVWGP

Amino acid data

ProtScale

Disclaimer: Hydropathy plot is not available for AAPeptide241 as the peptide length is less than 9 amino acid residues

Atomic information

3D Structure

Structural Representation of AAPeptide241

Amino acid data

Secondary structure fraction