AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide217

The Peptide Card page for AAPeptide217 gives textual and graphical visualizations of the properties of AAPeptide217. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide217.
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AAP ID	AAPeptide217
Peptide name	Agaricus blazei polypeptide (ABp)
PubMed/Patent ID	33200472
Origin	Natural
Source of Origin	Agaricus blazei
Condition addressed	D-Galactose induced aging
Experiment type	In vivo
Cell lines/Animal model	ICR mice
Intervention	Administartion of the peptide after D-galactose in mice
Experiment methods	Morris water maze test, Immunofluorescence dual staining of brain tissue (BrdU), qRT-PCR, Western Blot, MDA, CAT & T-AOC antioxidant enzyme activity, Reactive oxygen species (ROS) Assay
Patient group	NA
Markers used	NA
Mechanism of action	Improves the oxidative stress injury and exerts an anti-aging effect

Molecular weight	3135.949
Peptide length	25
Instability index	91.020
Aromaticity	0.080
Aliphaticity	0.080
Reduced molecular extinction coeffecient	6990
Oxidized molecular extinction coeffecient	6990
Isoelectric point	4.059
Composition of positively charged residues	0.160
Composition of negatively charged residues	0.520
Composition of neutral charged residues	0.320
Composition of residues polar residues	0.160
Composition of residues non-polar residues	0.120
Composition of residues having cyclic side chain	0.080
Composition of acidic residues	0.520
Composition of basic residues	0.160
Composition of residues having cyclic side chain	0.080
Composition of hydroxylic residues	0.120
Composition of residue in buried solvent accessibility	0.040
Composition of residue in exposed solvent accessibility	0.640
Composition of residue in intermediate solvent accessibility	0.400

AAPeptide217 :

EHEEHEEHEEHEPEDDPNSSEESYW

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide217

Amino acid data

Secondary structure fraction