AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide216

The Peptide Card page for AAPeptide216 gives textual and graphical visualizations of the properties of AAPeptide216. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide216.
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AAP ID	AAPeptide216
Peptide name	NA
PubMed/Patent ID	US 11103436 B2
Origin	Synthetic
Source of Origin	NA
Condition addressed	Skin aging, Anti-aging component of functional food
Experiment type	In vitro
Cell lines/Animal model	Mouse fibroblast NIH3T3 cell line, Human keratinocyte HaCaT cell line
Intervention	Cells were treated with the peptide
Experiment methods	MTT Cytotoxicity Assay, ELISA
Patient group	NA
Markers used	Collagen1a, Fibronectin, and Elastin, AQP3 (Aquaporin3) and SIRT1
Mechanism of action	Improves skin condition, Treats skin condition

Molecular weight	1216.300
Peptide length	11
Instability index	41.100
Aromaticity	0.091
Aliphaticity	0.455
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	4.679
Composition of positively charged residues	0.182
Composition of negatively charged residues	0.273
Composition of neutral charged residues	0.545
Composition of residues polar residues	0.000
Composition of residues non-polar residues	0.545
Composition of residues having cyclic side chain	0.182
Composition of acidic residues	0.273
Composition of basic residues	0.182
Composition of residues having cyclic side chain	0.182
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.364
Composition of residue in exposed solvent accessibility	0.545
Composition of residue in intermediate solvent accessibility	0.182

AAPeptide216 :

EDEFKPPAAGR

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide216

Amino acid data

Secondary structure fraction