AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide214

The Peptide Card page for AAPeptide214 gives textual and graphical visualizations of the properties of AAPeptide214. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide214.
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AAP ID	AAPeptide214
Peptide name	Kisspeptin 10
PubMed/Patent ID	33182726
Origin	Synthetic
Source of Origin	NA
Condition addressed	Skin aging
Experiment type	In vitro, Ex vivo
Cell lines/Animal model	Human dermal fibroblast (Hs68)
Intervention	Cells were treated with the peptide
Experiment methods	qRT-PCR, ELISA, Immunostaining, Measurements of Epidermis Thickness
Patient group	Human skin tissue from a woman donor of 38 years of age
Markers used	NA
Mechanism of action	Suppresses UV-induced 11β-HSD1 stimulation leading to a regulation of skin aging related genes and rescues the skin structure against UV irradiation, Inhibits the gene expression of stress related skin aging

Molecular weight	1303.423
Peptide length	10
Instability index	30.230
Aromaticity	0.400
Aliphaticity	0.200
Reduced molecular extinction coeffecient	6990
Oxidized molecular extinction coeffecient	6990
Isoelectric point	8.748
Composition of positively charged residues	0.100
Composition of negatively charged residues	0.000
Composition of neutral charged residues	0.900
Composition of residues polar residues	0.200
Composition of residues non-polar residues	0.500
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.000
Composition of basic residues	0.100
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.100
Composition of residue in buried solvent accessibility	0.500
Composition of residue in exposed solvent accessibility	0.200
Composition of residue in intermediate solvent accessibility	0.200

AAPeptide214 :

YNWNSFGLRF

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide214

Amino acid data

Secondary structure fraction