AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide212

The Peptide Card page for AAPeptide212 gives textual and graphical visualizations of the properties of AAPeptide212. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide212.
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AAP ID	AAPeptide212
Peptide name	Keramin2 peptide
PubMed/Patent ID	US 2020/0289526 A1
Origin	Synthetic
Source of Origin	NA
Condition addressed	Skin aging
Experiment type	In vitro
Cell lines/Animal model	HaCaT keratinocytes, Human Hair Dermal Papilla Cells (HHDP Cells)
Intervention	Cells were treated with the peptide
Experiment methods	Sulfohodomine B (SRB) calorimetric assay, Western blot, Skin Permeability Test using HPLC
Patient group	NA
Markers used	beta-catenin, DKK-1 (hair loss protein)
Mechanism of action	Has excellent physiological activities such as preventing hair loss, promoting hair growth, promoting cell growth, etc , but also has excellent stability in water and skin permeability

Molecular weight	1191.338
Peptide length	10
Instability index	10.160
Aromaticity	0.200
Aliphaticity	0.200
Reduced molecular extinction coeffecient	6990
Oxidized molecular extinction coeffecient	6990
Isoelectric point	10.001
Composition of positively charged residues	0.400
Composition of negatively charged residues	0.000
Composition of neutral charged residues	0.600
Composition of residues polar residues	0.300
Composition of residues non-polar residues	0.300
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.000
Composition of basic residues	0.400
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.200
Composition of residue in buried solvent accessibility	0.300
Composition of residue in exposed solvent accessibility	0.300
Composition of residue in intermediate solvent accessibility	0.400

AAPeptide212 :

YKSKKGGWTH

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide212

Amino acid data

Secondary structure fraction