AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide210

The Peptide Card page for AAPeptide210 gives textual and graphical visualizations of the properties of AAPeptide210. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide210.
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AAP ID	AAPeptide210
Peptide name	Pentapeptide-18
PubMed/Patent ID	31937863
Origin	Synthetic
Source of Origin	NA
Condition addressed	Melanogenesis
Experiment type	In vitro
Cell lines/Animal model	Human melanoma cell line (MNT-1), RAW 264.7, Human dermal fibroblasts (NHDF)
Intervention	Cells were treated with the peptide
Experiment methods	qRT-PCR, Immunostaining, L-DOPA tyrosinase activity assay, Quantification of melanin, MTT Cytotoxicity Assay, Histopathology
Patient group	NA
Markers used	NA
Mechanism of action	Inhibits melanin synthesis

Molecular weight	569.649
Peptide length	5
Instability index	55.360
Aromaticity	0.400
Aliphaticity	0.600
Reduced molecular extinction coeffecient	1490
Oxidized molecular extinction coeffecient	1490
Isoelectric point	5.524
Composition of positively charged residues	0.000
Composition of negatively charged residues	0.000
Composition of neutral charged residues	1.000
Composition of residues polar residues	0.200
Composition of residues non-polar residues	0.800
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.000
Composition of basic residues	0.000
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.800
Composition of residue in exposed solvent accessibility	0.000
Composition of residue in intermediate solvent accessibility	0.200

AAPeptide210 :

YAGFL

Amino acid data

ProtScale

Disclaimer: Hydropathy plot is not available for AAPeptide210 as the peptide length is less than 9 amino acid residues

Atomic information

3D Structure

Structural Representation of AAPeptide210

Amino acid data

Secondary structure fraction