AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide195

The Peptide Card page for AAPeptide195 gives textual and graphical visualizations of the properties of AAPeptide195. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide195.
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AAP IDAAPeptide195
Peptide nameNA
PubMed/Patent IDUS 10729636 B2
OriginSynthetic
Source of OriginNA
Condition addressedSkin aging
Experiment typeIn vitro, In vivo
Cell lines/Animal modelHuman Dermal Fibroblasts (HDF), Human keratinocytes, Human Skeletal Muscle Cells (HSkMC), KK.Cg-Ay/J (KKAY mouse)
InterventionCells were treated with the peptide, Subcutaneous injection of the peptide
Experiment methodsBrdU Cell Proliferation Assay, Collagen Production Assay, Glucose Uptake Assay, Elastin Production Assay, GLUT-4 Translocation using ELISA, Muscle Protein Synthesis (Phospho-mTOR Assay), Muscle protein synthesis (puromycin) assay, Phospho-Acetyl-CoA Carboxylate (Ser 79) ELISA, Phospho-Akt1 ELISA, Phospho-AMPK alpha ELISA, Blood glucose level and body weight estimation of KKAY mouse
Patient groupNA
Markers usedNA
Mechanism of actionImproves fine lines, wrinkles, dryness reducing redness and irritation
Molecular weight1270.477
Peptide length11
Instability index-8.100
Aromaticity0.091
Aliphaticity0.455
Reduced molecular extinction coeffecient5500
Oxidized molecular extinction coeffecient5500
Isoelectric point8.498
Composition of positively charged residues0.273
Composition of negatively charged residues0.182
Composition of neutral charged residues0.545
Composition of residues polar residues0.000
Composition of residues non-polar residues0.545
Composition of residues having cyclic side chain0.091
Composition of acidic residues0.182
Composition of basic residues0.273
Composition of residues having cyclic side chain0.091
Composition of hydroxylic residues0.000
Composition of residue in buried solvent accessibility0.455
Composition of residue in exposed solvent accessibility0.545
Composition of residue in intermediate solvent accessibility0.091

AAPeptide195 :
WKDEAGKPLVK

Amino acid data
ProtScale
Atomic information


3D Structure

Structural Representation of AAPeptide195

Amino acid data
Secondary structure fraction