AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide194

The Peptide Card page for AAPeptide194 gives textual and graphical visualizations of the properties of AAPeptide194. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide194.
To obtain further details, refer to the Help page.

AAP ID	AAPeptide194
Peptide name	Acetylcholine receptor-binding peptide
PubMed/Patent ID	US 2020/0123199 A1
Origin	Synthetic
Source of Origin	NA
Condition addressed	Skin aging
Experiment type	NA
Cell lines/Animal model	NA
Intervention	NA
Experiment methods	ELISA, Surface plasmon resonance (SPR) experiment
Patient group	NA
Markers used	NA
Mechanism of action	Peptides according to the present disclosure suppress secretion of acetylcholine by having a high binding strength with an acetylcholine receptor, thereby strongly binding the peptides to acetylcholine Therefore, a cosmetic composition and a pharmaceutical composition comprising peptides according to the present disclosure as an active ingredient exhibit an excellent wrinkle ameliorating effect

Molecular weight	1160.326
Peptide length	10
Instability index	-39.990
Aromaticity	0.100
Aliphaticity	0.300
Reduced molecular extinction coeffecient	5500
Oxidized molecular extinction coeffecient	5500
Isoelectric point	11.166
Composition of positively charged residues	0.300
Composition of negatively charged residues	0.000
Composition of neutral charged residues	0.700
Composition of residues polar residues	0.200
Composition of residues non-polar residues	0.400
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.000
Composition of basic residues	0.300
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.200
Composition of residue in buried solvent accessibility	0.400
Composition of residue in exposed solvent accessibility	0.300
Composition of residue in intermediate solvent accessibility	0.200

AAPeptide194 :

TWKGKGTLNR

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide194

Amino acid data

Secondary structure fraction