AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide189

The Peptide Card page for AAPeptide189 gives textual and graphical visualizations of the properties of AAPeptide189. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide189.
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AAP ID	AAPeptide189
Peptide name	WINT peptide
PubMed/Patent ID	US 2020/0289526 A1
Origin	Synthetic
Source of Origin	NA
Condition addressed	Skin aging
Experiment type	In vitro
Cell lines/Animal model	HaCaT keratinocytes, Human Hair Dermal Papilla Cells (HHDP Cells)
Intervention	Cells were treated with the peptide
Experiment methods	Sulfohodomine B (SRB) calorimetric assay, Western blot, Skin Permeability Test using HPLC
Patient group	NA
Markers used	beta-catenin, DKK-1 (hair loss protein)
Mechanism of action	Has excellent physiological activities such as preventing hair loss, promoting hair growth, promoting cell growth, etc, but also has excellent stability in water and skin permeability

Molecular weight	1287.476
Peptide length	10
Instability index	60.860
Aromaticity	0.000
Aliphaticity	0.100
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	125
Isoelectric point	9.023
Composition of positively charged residues	0.400
Composition of negatively charged residues	0.100
Composition of neutral charged residues	0.500
Composition of residues polar residues	0.400
Composition of residues non-polar residues	0.100
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.100
Composition of basic residues	0.400
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.100
Composition of residue in buried solvent accessibility	0.300
Composition of residue in exposed solvent accessibility	0.200
Composition of residue in intermediate solvent accessibility	0.200

AAPeptide189 :

RQTRVERCHC

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide189

Amino acid data

Secondary structure fraction