AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide169

The Peptide Card page for AAPeptide169 gives textual and graphical visualizations of the properties of AAPeptide169. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide169.
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AAP ID	AAPeptide169
Peptide name	PEP
PubMed/Patent ID	32419813
Origin	Natural
Source of Origin	Trapa japonica
Condition addressed	Skin aging
Experiment type	In vitro, Randomized clinical trial
Cell lines/Animal model	Human keratinocyte-derived (HaCaT) cells, Human dermal fibroblasts (HDFs)
Intervention	Cells were treated with the peptide, Topical application of the formulation
Experiment methods	WST1 Assay, ELISA, Cell migration assay
Patient group	Women aged 41 to 57 years
Markers used	NA
Mechanism of action	Exerts an effect on cell proliferation and collagen synthesis by decreasing the mRNA expression of TNF-α-induced MMP-1 and MMP-9 in HDFs, Shows potential as an anti skin-aging product which may be used in the cosmetic industry

Molecular weight	341.360
Peptide length	3
Instability index	128.800
Aromaticity	0.000
Aliphaticity	0.667
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	4.050
Composition of positively charged residues	0.000
Composition of negatively charged residues	0.333
Composition of neutral charged residues	0.667
Composition of residues polar residues	0.000
Composition of residues non-polar residues	0.667
Composition of residues having cyclic side chain	0.667
Composition of acidic residues	0.333
Composition of basic residues	0.000
Composition of residues having cyclic side chain	0.667
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.000
Composition of residue in exposed solvent accessibility	1.000
Composition of residue in intermediate solvent accessibility	0.667

AAPeptide169 :

PEP

Amino acid data

ProtScale

Disclaimer: Hydropathy plot is not available for AAPeptide169 as the peptide length is less than 9 amino acid residues

Atomic information

3D Structure

Structural Representation of AAPeptide169

Amino acid data

Secondary structure fraction