AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide161

The Peptide Card page for AAPeptide161 gives textual and graphical visualizations of the properties of AAPeptide161. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide161.
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AAP IDAAPeptide161
Peptide nameA. japonicus protein hydrolyzate (AjPH)
PubMed/Patent ID32520032
OriginNatural
Source of OriginApostichopus japonicus
Condition addressedAnti aging component of functional food
Experiment typeIn vitro, In vivo
Cell lines/Animal modelRat pheochromocytoma cell line PC12, Caenorhabditis elegans (wild-type N2) , Escherichia coli (OP50 and NA22
InterventionCells and nematodes were treated with the peptide
Experiment methodsCAT and SOD antioxidant enzyme activity, MDA content assay, DCFH-DA ROS assay, CCK-8 cell viability assay, DPPH radical scavenging assay, Age pigment accumulation assay in C. elegans, Lifespan analysis of C. elegans, Food clearance assay in C. elegans, Determination of body length and brood size of C. elegans
Patient groupNA
Markers usedNA
Mechanism of actionReduces the ROS level, Decreases the accumulation of age pigments and extends the adult lifespan, Shows anti-aging effect without sacrificing growth and reproduction"
Molecular weight1563.712
Peptide length15
Instability index63.527
Aromaticity0.067
Aliphaticity0.600
Reduced molecular extinction coeffecient5500
Oxidized molecular extinction coeffecient5500
Isoelectric point6.002
Composition of positively charged residues0.067
Composition of negatively charged residues0.067
Composition of neutral charged residues0.867
Composition of residues polar residues0.200
Composition of residues non-polar residues0.667
Composition of residues having cyclic side chain0.267
Composition of acidic residues0.067
Composition of basic residues0.067
Composition of residues having cyclic side chain0.267
Composition of hydroxylic residues0.133
Composition of residue in buried solvent accessibility0.400
Composition of residue in exposed solvent accessibility0.400
Composition of residue in intermediate solvent accessibility0.400

AAPeptide161 :
GPEPTGPTGAPQWLR

Amino acid data
ProtScale
Atomic information


3D Structure

Structural Representation of AAPeptide161

Amino acid data
Secondary structure fraction