AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide159

The Peptide Card page for AAPeptide159 gives textual and graphical visualizations of the properties of AAPeptide159. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide159.
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AAP ID	AAPeptide159
Peptide name	Nokkin peptide
PubMed/Patent ID	US 2020/0289526 A1
Origin	Synthetic
Source of Origin	NA
Condition addressed	Skin aging
Experiment type	In vitro
Cell lines/Animal model	HaCaT keratinocytes, Human Hair Dermal Papilla Cells (HHDP Cells)
Intervention	Cells were treated with the peptide
Experiment methods	Sulfohodomine B (SRB) calorimetric assay, Western blot, Skin Permeability Test using HPLC
Patient group	NA
Markers used	beta-catenin, DKK-1 (hair loss protein)
Mechanism of action	Has excellent physiological activities such as preventing hair loss, promoting hair growth, promoting cell growth, etc, Has excellent stability in water and skin permeability

Molecular weight	1250.318
Peptide length	12
Instability index	76.450
Aromaticity	0.000
Aliphaticity	0.583
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	4.834
Composition of positively charged residues	0.167
Composition of negatively charged residues	0.250
Composition of neutral charged residues	0.583
Composition of residues polar residues	0.000
Composition of residues non-polar residues	0.583
Composition of residues having cyclic side chain	0.083
Composition of acidic residues	0.250
Composition of basic residues	0.167
Composition of residues having cyclic side chain	0.083
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.500
Composition of residue in exposed solvent accessibility	0.333
Composition of residue in intermediate solvent accessibility	0.167

AAPeptide159 :

ELIEHGGGRPAD

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide159

Amino acid data

Secondary structure fraction