AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide151

The Peptide Card page for AAPeptide151 gives textual and graphical visualizations of the properties of AAPeptide151. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide151.
To obtain further details, refer to the Help page.

AAP ID	AAPeptide151
Peptide name	LDLR binding site containg 5-YHEDA (bs-5-YHEDA)
PubMed/Patent ID	31921964
Origin	Synthetic
Source of Origin	NA
Condition addressed	Brain aging
Experiment type	In vitro, In vivo
Cell lines/Animal model	Neuroblastoma cell line SH-sy5y, Human vascular endothelial cells (HECV)
Intervention	Cells were treated with the peptide
Experiment methods	Cell apoptosis assay, Hydroxyl radical measurement, Coimmunoprecipitation, Western Blotting, Immunohistochemical staining, Morris Water Maze Test, Functional brain magnetic resonance imaging assay, Hematologic analyses, TUNNEL Assay
Patient group	NA
Markers used	NA
Mechanism of action	Relieves senescence-induced inflammation

Molecular weight	4073.089
Peptide length	34
Instability index	64.106
Aromaticity	0.147
Aliphaticity	0.294
Reduced molecular extinction coeffecient	7450
Oxidized molecular extinction coeffecient	7450
Isoelectric point	4.318
Composition of positively charged residues	0.176
Composition of negatively charged residues	0.324
Composition of neutral charged residues	0.500
Composition of residues polar residues	0.206
Composition of residues non-polar residues	0.294
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.324
Composition of basic residues	0.176
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.029
Composition of residue in buried solvent accessibility	0.294
Composition of residue in exposed solvent accessibility	0.353
Composition of residue in intermediate solvent accessibility	0.353

AAPeptide151 :

YHEDAYHEDAYHEDAYHEDAYHEDAQSDIVAHLL

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide151

Amino acid data

Secondary structure fraction