AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide150

The Peptide Card page for AAPeptide150 gives textual and graphical visualizations of the properties of AAPeptide150. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide150.
To obtain further details, refer to the Help page.

AAP ID	AAPeptide150
Peptide name	5-YHEDA
PubMed/Patent ID	31921964
Origin	Synthetic
Source of Origin	NA
Condition addressed	Brain aging
Experiment type	In vitro, In vivo
Cell lines/Animal model	Neuroblastoma cell line SH-sy5y, Human vascular endothelial cells (HECV)
Intervention	Cells were treated with the peptide
Experiment methods	Cell apoptosis assay, Hydroxyl radical measurement, Coimmunoprecipitation, Western blot, Immunohistochemistry, Morris Water Maze Test, Functional brain magnetic resonance imaging assay, Hematologic analyses, TUNNEL Assay
Patient group	NA
Markers used	NA
Mechanism of action	Protects cells by reducing radicals, Binds LDLR and thus cross the BBB to enter the brain

Molecular weight	3095.974
Peptide length	25
Instability index	72.800
Aromaticity	0.200
Aliphaticity	0.200
Reduced molecular extinction coeffecient	7450
Oxidized molecular extinction coeffecient	7450
Isoelectric point	4.262
Composition of positively charged residues	0.200
Composition of negatively charged residues	0.400
Composition of neutral charged residues	0.400
Composition of residues polar residues	0.200
Composition of residues non-polar residues	0.200
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.400
Composition of basic residues	0.200
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.200
Composition of residue in exposed solvent accessibility	0.400
Composition of residue in intermediate solvent accessibility	0.400

AAPeptide150 :

YHEDAYHEDAYHEDAYHEDAYHEDA

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide150

Amino acid data

Secondary structure fraction