AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide149

The Peptide Card page for AAPeptide149 gives textual and graphical visualizations of the properties of AAPeptide149. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide149.
To obtain further details, refer to the Help page.

AAP ID	AAPeptide149
Peptide name	Calcitonin receptor derived polypeptide
PubMed/Patent ID	US 10294290 B2
Origin	Synthetic
Source of Origin	NA
Condition addressed	Bone aging
Experiment type	In vitro
Cell lines/Animal model	PC12 (rat adrenal pheochromocytoma) cells, MC3T3-E1 (chondrocyte preosteoblast) cells, hFOB (human fetal osteoblast) cells
Intervention	Cells were treated with the peptide
Experiment methods	Bone matrix formation assay, Immunostaining
Patient group	NA
Markers used	NA
Mechanism of action	Increases the production of bone matrix in both differentiating and terminally differentiated cells, Increases the levels of osteocalcin

Molecular weight	1718.956
Peptide length	12
Instability index	27.942
Aromaticity	0.333
Aliphaticity	0.167
Reduced molecular extinction coeffecient	16500
Oxidized molecular extinction coeffecient	16500
Isoelectric point	11.001
Composition of positively charged residues	0.167
Composition of negatively charged residues	0.000
Composition of neutral charged residues	0.833
Composition of residues polar residues	0.250
Composition of residues non-polar residues	0.500
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.000
Composition of basic residues	0.167
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.500
Composition of residue in exposed solvent accessibility	0.417
Composition of residue in intermediate solvent accessibility	0.000

AAPeptide149 :

WVQFKIQWNQRW

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide149

Amino acid data

Secondary structure fraction