AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide148

The Peptide Card page for AAPeptide148 gives textual and graphical visualizations of the properties of AAPeptide148. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide148.
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AAP IDAAPeptide148
Peptide nameCalcitonin receptor derived polypeptide
PubMed/Patent IDUS 10294290 B2
OriginSynthetic
Source of OriginNA
Condition addressedBone aging
Experiment typeIn vitro
Cell lines/Animal modelPC12 (rat adrenal pheochromocytoma) cells, MC3T3-E1 (chondrocyte preosteoblast) cells, hFOB (human fetal osteoblast) cells
InterventionCells were treated with the peptide
Experiment methodsBone matrix formation assay, Immunostaining
Patient groupNA
Markers usedNA
Mechanism of actionIncreases the production of bone matrix in both differentiating and terminally differentiated cells, Increases the levels of osteocalcin
Molecular weight1672.887
Peptide length12
Instability index18.492
Aromaticity0.333
Aliphaticity0.167
Reduced molecular extinction coeffecient16500
Oxidized molecular extinction coeffecient16500
Isoelectric point11.001
Composition of positively charged residues0.250
Composition of negatively charged residues0.000
Composition of neutral charged residues0.750
Composition of residues polar residues0.250
Composition of residues non-polar residues0.500
Composition of residues having cyclic side chain0.000
Composition of acidic residues0.000
Composition of basic residues0.250
Composition of residues having cyclic side chain0.000
Composition of hydroxylic residues0.083
Composition of residue in buried solvent accessibility0.500
Composition of residue in exposed solvent accessibility0.250
Composition of residue in intermediate solvent accessibility0.167

AAPeptide148 :
WAQFKIQWSHRW

Amino acid data
ProtScale
Atomic information


3D Structure

Structural Representation of AAPeptide148

Amino acid data
Secondary structure fraction