AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide146

The Peptide Card page for AAPeptide146 gives textual and graphical visualizations of the properties of AAPeptide146. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide146.
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AAP ID	AAPeptide146
Peptide name	NA
PubMed/Patent ID	US 2019/0153045 A1
Origin	Natural
Source of Origin	Oryza sativa
Condition addressed	Skin aging
Experiment type	In vitro, Ex vivo
Cell lines/Animal model	Skin fibroblasts derived healthy Caucasian females of different ages, Adult dermal fibroblasts, Human skin explants
Intervention	Cells were treated with the peptides
Experiment methods	Western Blot, Assessment of Deposition of Elastic Fibers, Immunostaining, Immunocytochemistry, Representative micrographs of 10-day old organ cultures of human skin explants
Patient group	Healthy Caucasian females of different ages, 44 year old woman
Markers used	Tropoeelastin
Mechanism of action	Increases production of elastic fibers by stromal cells isolated from human heart,Treating facial lines and wrinkles, Stimulates proliferation and migration of dermal fibroblasts into an area of skin

Molecular weight	514.572
Peptide length	6
Instability index	67.417
Aromaticity	0.000
Aliphaticity	0.833
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	5.495
Composition of positively charged residues	0.000
Composition of negatively charged residues	0.000
Composition of neutral charged residues	1.000
Composition of residues polar residues	0.167
Composition of residues non-polar residues	0.833
Composition of residues having cyclic side chain	0.167
Composition of acidic residues	0.000
Composition of basic residues	0.000
Composition of residues having cyclic side chain	0.167
Composition of hydroxylic residues	0.167
Composition of residue in buried solvent accessibility	0.667
Composition of residue in exposed solvent accessibility	0.167
Composition of residue in intermediate solvent accessibility	0.333

AAPeptide146 :

VGVSPG

Amino acid data

ProtScale

Disclaimer: Hydropathy plot is not available for AAPeptide146 as the peptide length is less than 9 amino acid residues

Atomic information

3D Structure

Structural Representation of AAPeptide146

Amino acid data

Secondary structure fraction