AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide139

The Peptide Card page for AAPeptide139 gives textual and graphical visualizations of the properties of AAPeptide139. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide139.
To obtain further details, refer to the Help page.

AAP ID	AAPeptide139
Peptide name	NA
PubMed/Patent ID	US 10246446 B2
Origin	Natural
Source of Origin	Mice
Condition addressed	Skin aging
Experiment type	In vitro, In vivo
Cell lines/Animal model	HEK293 cell line, Mice
Intervention	Cells were treated with the peptide, GHR knockout (GHRKO) mice and their age-matched wild type (WT) littermates
Experiment methods	Comet Assay, Slot-blot analysis
Patient group	NA
Markers used	NA
Mechanism of action	Attenuates the growth of GH, Attenuates changes in biomarkers associated with aging

Molecular weight	1322.460
Peptide length	12
Instability index	31.433
Aromaticity	0.000
Aliphaticity	0.583
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	4.050
Composition of positively charged residues	0.000
Composition of negatively charged residues	0.250
Composition of neutral charged residues	0.750
Composition of residues polar residues	0.167
Composition of residues non-polar residues	0.583
Composition of residues having cyclic side chain	0.250
Composition of acidic residues	0.250
Composition of basic residues	0.000
Composition of residues having cyclic side chain	0.250
Composition of hydroxylic residues	0.083
Composition of residue in buried solvent accessibility	0.333
Composition of residue in exposed solvent accessibility	0.583
Composition of residue in intermediate solvent accessibility	0.333

AAPeptide139 :

TVDEIVQPDPPI

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide139

Amino acid data

Secondary structure fraction