AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide129

The Peptide Card page for AAPeptide129 gives textual and graphical visualizations of the properties of AAPeptide129. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide129.
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AAP IDAAPeptide129
Peptide nameAnnexin A1 biomimetic short peptide (ANXA1sp)
PubMed/Patent IDUS 10172915 B2
OriginNatural
Source of OriginRat
Condition addressedAging-related diseases
Experiment typeIn vitro, In vivo
Cell lines/Animal modelAdult Rat Ventricular Cardiomyocytes (ARVCs), Male Sprague-Dawley (SD)
InterventionRat Model of Cardiopulmonary Bypass with Cardioplegic Arrest (CPB/CA) or Deep Hypothermic Circulatory Arrest (DHCA) were treated with the peptide, Cells were treated with the peptide
Experiment methodsWestern blot, Immunostaining, TUNEL assay
Patient groupNA
Markers usedSirt1
Mechanism of actionImproves mitochondrial fnctions
Molecular weight403.432
Peptide length3
Instability index6.667
Aromaticity0.333
Aliphaticity0.333
Reduced molecular extinction coeffecient5500
Oxidized molecular extinction coeffecient5500
Isoelectric point5.525
Composition of positively charged residues0.000
Composition of negatively charged residues0.000
Composition of neutral charged residues1.000
Composition of residues polar residues0.333
Composition of residues non-polar residues0.667
Composition of residues having cyclic side chain0.000
Composition of acidic residues0.000
Composition of basic residues0.000
Composition of residues having cyclic side chain0.000
Composition of hydroxylic residues0.000
Composition of residue in buried solvent accessibility0.667
Composition of residue in exposed solvent accessibility0.333
Composition of residue in intermediate solvent accessibility0.000

AAPeptide129 :
QAW

Amino acid data
ProtScale


Disclaimer: Hydropathy plot is not available for AAPeptide129 as the peptide length is less than 9 amino acid residues

Atomic information


3D Structure

Structural Representation of AAPeptide129

Amino acid data
Secondary structure fraction