AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide127

The Peptide Card page for AAPeptide127 gives textual and graphical visualizations of the properties of AAPeptide127. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide127.
To obtain further details, refer to the Help page.

AAP IDAAPeptide127
Peptide nameNA
PubMed/Patent IDUS 2019/0142723 A1,US 10660839 B2
OriginNatural
Source of OriginHuman and mouse
Condition addressedSkin aging
Experiment typeIn vitro
Cell lines/Animal modelHuman melanocytes (HEMn cells) , Mouse melanoma (B16 cells), Human fibroblasts,Mouse melanoma (B16 cells), Normal human melanocytes (HEMn cells), Human keratinocytes
InterventionCells were treated with the peptide
Experiment methodsMelanogenesis, Pro-pigmenting and pro-collagen dual activity by immunostaining, BCA protein assay, Assayed by spectrophotometry
Patient groupNA
Markers usedNA
Mechanism of actionTreates spots, wrinkles, and fine lines, the default of complexion homogeneity, Stimulates the synthesis of collagen to obtain a volumizing effect, the loss of skin hydration by improving the skin barrier
Molecular weight246.326
Peptide length2
Instability index-32.700
Aromaticity0.000
Aliphaticity0.500
Reduced molecular extinction coeffecient0
Oxidized molecular extinction coeffecient0
Isoelectric point5.955
Composition of positively charged residues0.000
Composition of negatively charged residues0.000
Composition of neutral charged residues1.000
Composition of residues polar residues0.000
Composition of residues non-polar residues1.000
Composition of residues having cyclic side chain0.500
Composition of acidic residues0.000
Composition of basic residues0.000
Composition of residues having cyclic side chain0.500
Composition of hydroxylic residues0.000
Composition of residue in buried solvent accessibility0.000
Composition of residue in exposed solvent accessibility0.500
Composition of residue in intermediate solvent accessibility1.000

AAPeptide127 :
PM

Amino acid data
ProtScale


Disclaimer: Hydropathy plot is not available for AAPeptide127 as the peptide length is less than 9 amino acid residues

Atomic information


3D Structure

Structural Representation of AAPeptide127

Amino acid data
Secondary structure fraction