AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide126

The Peptide Card page for AAPeptide126 gives textual and graphical visualizations of the properties of AAPeptide126. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide126.
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AAP IDAAPeptide126
Peptide nameTetrapeptide,
PubMed/Patent IDUS 2020/0022890 A1,US 10463585 B2
OriginNatural
Source of OriginHuman
Condition addressedSkin aging
Experiment typeIn vitro
Cell lines/Animal modelHuman cadaver skin
InterventionSplit-thickness human cadaver skin was radiolabeled with the peptide,Topical application of cosmetic composition
Experiment methodsSkin Penetration Test,Titration
Patient groupHuman cadaver
Markers usedNA
Mechanism of actionTreat or reduce appearance of age spots , Improve skin tone evenness,treatment of skin pigmentation by interfering with the keratinocyte to melanocyte signaling processes
Molecular weight500.589
Peptide length4
Instability index7.500
Aromaticity0.000
Aliphaticity0.250
Reduced molecular extinction coeffecient0
Oxidized molecular extinction coeffecient0
Isoelectric point9.006
Composition of positively charged residues0.500
Composition of negatively charged residues0.250
Composition of neutral charged residues0.250
Composition of residues polar residues0.000
Composition of residues non-polar residues0.250
Composition of residues having cyclic side chain0.250
Composition of acidic residues0.250
Composition of basic residues0.500
Composition of residues having cyclic side chain0.250
Composition of hydroxylic residues0.000
Composition of residue in buried solvent accessibility0.000
Composition of residue in exposed solvent accessibility1.000
Composition of residue in intermediate solvent accessibility0.250

AAPeptide126 :
PKEK

Amino acid data
ProtScale


Disclaimer: Hydropathy plot is not available for AAPeptide126 as the peptide length is less than 9 amino acid residues

Atomic information


3D Structure

Structural Representation of AAPeptide126

Amino acid data
Secondary structure fraction