AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide124

The Peptide Card page for AAPeptide124 gives textual and graphical visualizations of the properties of AAPeptide124. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide124.
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AAP IDAAPeptide124
Peptide nameTetrapeptide
PubMed/Patent IDUS 2020/0022890 A1,US 10376557 B2,US 10463585 B2
OriginNatural
Source of OriginHuman
Condition addressedSkin aging
Experiment typeIn vitro
Cell lines/Animal modelHuman cadaver skin, Human dermal fibroblast, Human skin epithelial cells (CRL-2592)
InterventionSplit-thickness human cadaver skin was radiolabeled with the peptide,Cells were treated with the peptide,Topical application of cosmetic composition
Experiment methodsSkin Penetration Test,Titration,??
Patient groupHuman cadaver
Markers usedNA
Mechanism of actionReduces the appearance of age spots, Improves skin tone unevenness, Wound healing, Repaires damaged skin, Maintains healthy skin, Treats skin pigmentation by interfering with the keratinocyte to melanocyte signaling processes
Molecular weight366.412
Peptide length4
Instability index55.650
Aromaticity0.000
Aliphaticity1.000
Reduced molecular extinction coeffecient0
Oxidized molecular extinction coeffecient0
Isoelectric point5.955
Composition of positively charged residues0.000
Composition of negatively charged residues0.000
Composition of neutral charged residues1.000
Composition of residues polar residues0.000
Composition of residues non-polar residues1.000
Composition of residues having cyclic side chain0.750
Composition of acidic residues0.000
Composition of basic residues0.000
Composition of residues having cyclic side chain0.750
Composition of hydroxylic residues0.000
Composition of residue in buried solvent accessibility0.250
Composition of residue in exposed solvent accessibility0.750
Composition of residue in intermediate solvent accessibility0.750

AAPeptide124 :
PGPP

Amino acid data
ProtScale


Disclaimer: Hydropathy plot is not available for AAPeptide124 as the peptide length is less than 9 amino acid residues

Atomic information


3D Structure

Structural Representation of AAPeptide124

Amino acid data
Secondary structure fraction