AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide111

The Peptide Card page for AAPeptide111 gives textual and graphical visualizations of the properties of AAPeptide111. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide111.
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AAP ID	AAPeptide111
Peptide name	NA
PubMed/Patent ID	US 10233215 B2,US 2019/0002505 A1
Origin	Synthetic
Source of Origin	NA
Condition addressed	Alopecia caused by aging
Experiment type	In vitro, Ex vivo
Cell lines/Animal model	Human monocyte cell line THP-1, Human hair follicle dermal papilla cells, Mouse Macrophage Cells (RAW 264.7), Mouse Bone Marrow-Derived Dendritic Cells
Intervention	Cells were treated with the peptide
Experiment methods	ELISA
Patient group	NA
Markers used	IL-1β, IL-18, TNFα and IL-8,IL-1β, IL-18, TNFα and IL-7
Mechanism of action	Has immunostimulatory effect and therefore can be used as an immunostimulant, Can be used as an ingredient of cosmetics, quasi drugs, medicinal drugs, foods and drinks and dietary supplements intended to promote hair growth or regrowth

Molecular weight	1617.045
Peptide length	12
Instability index	65.400
Aromaticity	0.000
Aliphaticity	0.333
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	12.000
Composition of positively charged residues	0.667
Composition of negatively charged residues	0.000
Composition of neutral charged residues	0.333
Composition of residues polar residues	0.000
Composition of residues non-polar residues	0.333
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.000
Composition of basic residues	0.667
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.333
Composition of residue in exposed solvent accessibility	0.250
Composition of residue in intermediate solvent accessibility	0.083

AAPeptide111 :

LHRLKRLRKRLK

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide111

Amino acid data

Secondary structure fraction