AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide091

The Peptide Card page for AAPeptide091 gives textual and graphical visualizations of the properties of AAPeptide091. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide091.
To obtain further details, refer to the Help page.

AAP IDAAPeptide091
Peptide nameRTE62G (pep_RTE62G)
PubMed/Patent IDUS 10925922 B2, EP 3590523 A1,US 2019/0321436 A1,32453870
OriginNatural
Source of OriginPisum sativum
Condition addressedSkin aging
Experiment typeIn vitro, Randomized clinical trial
Cell lines/Animal modelHuman Dermal Fibroblasts (HDF—Sigma 10605a), Immortalised human keratinocytes (HaCaT)
InterventionCells were treated with the peptide, Topical application of the formulation,Cells were treated with the peptide
Experiment methodsCollagen Production Assay, Elastin Production Assay, Elastin and Cell Proliferation Assay, BrdU cell proliferation assay, Scratch Wound Assay, Elastin and hydroxyproline ELISA, Immunofluroscence staining, MTT Cell Proliferation Assay
Patient groupFemale volunteers (phototype I to IV; aged 45-65) with visible periorbital wrinkles.",Human
Markers usedNA
Mechanism of actionTreats diseases or conditions characterised by damaged epithelial cells or tissue such as colon cancer and peripheral inflammatory disorders, and wound treatment, Prevents skin aging, Stimulates key dermal proteins, implicated in skin aging, namely collagen, elastin and fibrillin
Molecular weight1819.085
Peptide length16
Instability index68.875
Aromaticity0.125
Aliphaticity0.438
Reduced molecular extinction coeffecient2980
Oxidized molecular extinction coeffecient2980
Isoelectric point6.747
Composition of positively charged residues0.125
Composition of negatively charged residues0.062
Composition of neutral charged residues0.812
Composition of residues polar residues0.312
Composition of residues non-polar residues0.500
Composition of residues having cyclic side chain0.188
Composition of acidic residues0.062
Composition of basic residues0.125
Composition of residues having cyclic side chain0.188
Composition of hydroxylic residues0.188
Composition of residue in buried solvent accessibility0.250
Composition of residue in exposed solvent accessibility0.312
Composition of residue in intermediate solvent accessibility0.625

AAPeptide091 :
HGPVEMPYTLLYPSSK

Amino acid data
ProtScale
Atomic information


3D Structure

Structural Representation of AAPeptide091

Amino acid data
Secondary structure fraction