AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide072

The Peptide Card page for AAPeptide072 gives textual and graphical visualizations of the properties of AAPeptide072. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide072.
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AAP ID	AAPeptide072
Peptide name	Metallothioneins (MT) peptide fragments
PubMed/Patent ID	US 10100100 B2
Origin	Natural
Source of Origin	NA
Condition addressed	Aging-related degenerative diseases
Experiment type	In vitro
Cell lines/Animal model	Primary CGN cultures
Intervention	Cells were treated with the peptide
Experiment methods	Cell Survival Assay, TUNEL Assay
Patient group	NA
Markers used	NA
Mechanism of action	Stimulates neuronal cell differentiation, neuronal cell survival and neural plasticity associated with learning and memory, Inhibites the oxidative stress and inflammatory responses, Modulates survival and neuroprotection, Promotes the effects of growth factors and regulatory molecules and their receptors

Molecular weight	1402.552
Peptide length	14
Instability index	46.329
Aromaticity	0.000
Aliphaticity	0.143
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	125
Isoelectric point	8.840
Composition of positively charged residues	0.214
Composition of negatively charged residues	0.071
Composition of neutral charged residues	0.714
Composition of residues polar residues	0.571
Composition of residues non-polar residues	0.143
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.071
Composition of basic residues	0.214
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.429
Composition of residue in buried solvent accessibility	0.286
Composition of residue in exposed solvent accessibility	0.286
Composition of residue in intermediate solvent accessibility	0.429

AAPeptide072 :

SAGSCKCKESKSTS

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide072

Amino acid data

Secondary structure fraction