AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide071


The Peptide Card page for AAPeptide071 gives textual and graphical visualizations of the properties of AAPeptide071. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide071.
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AAP IDAAPeptide071
Peptide namePhycobiliproteins (PBPs)
PubMed/Patent ID29717771
OriginNatural
Source of OriginPorphyra purpurea
Condition addressedCell aging
Experiment typeIn vitro
Cell lines/Animal modelHepG2 human hepatoblastoma cell line
InterventionCells were treated with the peptide
Experiment methodsFluorescein diacetate (FDA) and propidium iodide (PI) cell viability measurement, DCF-DA ROS assay, Western blot, Bicinchoninic acid assay (Protein asay)
Patient groupNA
Markers usedNA
Mechanism of actionUpregulates the protein expression of p-Nrf2 and antioxidant enzymes, Attenuates H2O2-induced oxidative stress in the cells
Molecular weight2127.376
Peptide length19
Instability index34.274
Aromaticity0.105
Aliphaticity0.474
Reduced molecular extinction coeffecient2980
Oxidized molecular extinction coeffecient2980
Isoelectric point4.558
Composition of positively charged residues0.105
Composition of negatively charged residues0.158
Composition of neutral charged residues0.737
Composition of residues polar residues0.263
Composition of residues non-polar residues0.474
Composition of residues having cyclic side chain0.053
Composition of acidic residues0.158
Composition of basic residues0.105
Composition of residues having cyclic side chain0.053
Composition of hydroxylic residues0.105
Composition of residue in buried solvent accessibility0.474
Composition of residue in exposed solvent accessibility0.211
Composition of residue in intermediate solvent accessibility0.263

AAPeptide071 :
RYVSYALLAGDPSVLEDRC

Amino acid data
ProtScale
Atomic information


3D Structure

Structural Representation of AAPeptide071

Amino acid data
Secondary structure fraction