AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide049

The Peptide Card page for AAPeptide049 gives textual and graphical visualizations of the properties of AAPeptide049. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide049.
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AAP ID	AAPeptide049
Peptide name	NA
PubMed/Patent ID	US 10045925 B2
Origin	Synthetic
Source of Origin	NA
Condition addressed	Skin aging
Experiment type	In vitro, Randomized clinical trial
Cell lines/Animal model	Human keratinocytes (HaCaT)
Intervention	Cells were treated with the peptide, Topical application of the formulation
Experiment methods	Assessment of face wrinkles, skin radiance/luminosity and skin lightness, GSH, LDH Antioxidant enzyme activity, Stability Testing
Patient group	Female subjects, aged 35-55 years
Markers used	Lactate dehydrogenase (LDH, a general cytotoxicity marker)
Mechanism of action	Skin brightening, Improves hydration and firmness

Molecular weight	456.497
Peptide length	4
Instability index	36.800
Aromaticity	0.000
Aliphaticity	0.500
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	9.750
Composition of positively charged residues	0.250
Composition of negatively charged residues	0.000
Composition of neutral charged residues	0.750
Composition of residues polar residues	0.250
Composition of residues non-polar residues	0.500
Composition of residues having cyclic side chain	0.250
Composition of acidic residues	0.000
Composition of basic residues	0.250
Composition of residues having cyclic side chain	0.250
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.250
Composition of residue in exposed solvent accessibility	0.500
Composition of residue in intermediate solvent accessibility	0.250

AAPeptide049 :

GQPR

Amino acid data

ProtScale

Disclaimer: Hydropathy plot is not available for AAPeptide049 as the peptide length is less than 9 amino acid residues

Atomic information

3D Structure

Structural Representation of AAPeptide049

Amino acid data

Secondary structure fraction