AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide012

The Peptide Card page for AAPeptide012 gives textual and graphical visualizations of the properties of AAPeptide012. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide012.
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AAP ID	AAPeptide012
Peptide name	Acein
PubMed/Patent ID	27027724
Origin	Synthetic
Source of Origin	NA
Condition addressed	Aging induced by senescent cells development
Experiment type	In vitro, In vivo
Cell lines/Animal model	Guinea pigs, Sprague–Dawley rats
Intervention	Microinjection of the peptide
Experiment methods	Rotational behaviour assessment of animals, Stimulation of striatal dopamine release by acein, Western blot, Silver staining
Patient group	NA
Markers used	NA
Mechanism of action	Able to induce in vivo and in vitro stimulation of dopamine release from rat brain tissue

Molecular weight	933.059
Peptide length	9
Instability index	30.289
Aromaticity	0.111
Aliphaticity	0.444
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	9.180
Composition of positively charged residues	0.111
Composition of negatively charged residues	0.000
Composition of neutral charged residues	0.889
Composition of residues polar residues	0.333
Composition of residues non-polar residues	0.556
Composition of residues having cyclic side chain	0.222
Composition of acidic residues	0.000
Composition of basic residues	0.111
Composition of residues having cyclic side chain	0.222
Composition of hydroxylic residues	0.333
Composition of residue in buried solvent accessibility	0.333
Composition of residue in exposed solvent accessibility	0.333
Composition of residue in intermediate solvent accessibility	0.556

AAPeptide012 :

PPTTTKFAA

Amino acid data

ProtScale

Atomic information

3D Structure

Structural Representation of AAPeptide012

Amino acid data

Secondary structure fraction