AagingBase | Database of anti-aging peptide

Peptide Card for AAPeptide004

The Peptide Card page for AAPeptide004 gives textual and graphical visualizations of the properties of AAPeptide004. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide004.
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AAP IDAAPeptide004
Peptide nameOctanoyl Carnosine,Carnosine
PubMed/Patent ID25055965,US 11331305 B2,US 2020/0093799 A1
OriginNatural
Source of OriginHuman
Condition addressedD-galactose induced aging, Anti aging component of functional food, Skin aging
Experiment typeIn vitro, In vivo, Randomized clinical trial
Cell lines/Animal modelBALB/c mice, Normal human dermal fibroblasts (NHDF)
InterventionCells were treated with the peptide, Topical application of the formulation,Oral administration of the peptide to the mice after D-galactose subcutaneous injection.,Cells were treated with the peptide
Experiment methodsMTT cytotoxicity assay, ELISA, Wound Healing Studies, Skin Atrophy Studies, Vulvovaginal Atrophy Studies, qRT-PCR, Morris water maze test, Blood parameter analysis, Histopathology, Immunostaining
Patient groupHuman
Markers usedMDA, GSH, ACE,collagen I, collagen III, collagen VII, elastin
Mechanism of actionAttenuates the oxidative stress, Improves spatial memory and learning dysfunctions, Stimulates the production of extracellular matrix components in skin or epithelial cells
Molecular weight226.232
Peptide length2
Instability index-37.450
Aromaticity0.000
Aliphaticity0.500
Reduced molecular extinction coeffecient0
Oxidized molecular extinction coeffecient0
Isoelectric point6.786
Composition of positively charged residues0.500
Composition of negatively charged residues0.000
Composition of neutral charged residues0.500
Composition of residues polar residues0.000
Composition of residues non-polar residues0.500
Composition of residues having cyclic side chain0.000
Composition of acidic residues0.000
Composition of basic residues0.500
Composition of residues having cyclic side chain0.000
Composition of hydroxylic residues0.000
Composition of residue in buried solvent accessibility0.500
Composition of residue in exposed solvent accessibility0.000
Composition of residue in intermediate solvent accessibility0.500

AAPeptide004 :
AH

Amino acid data
ProtScale


Disclaimer: Hydropathy plot is not available for AAPeptide004 as the peptide length is less than 9 amino acid residues

Atomic information


3D Structure

Structural Representation of AAPeptide004

Amino acid data
Secondary structure fraction