AagingBase | Database of anti-aging peptide

AagingBase: Database of anti-aging peptides A manually curated comprehensive database for anti-aging peptides

Peptide Card for AAPeptide002

The Peptide Card page for AAPeptide002 gives textual and graphical visualizations of the properties of AAPeptide002. The users can find all the literature informations collected from scholarly articles and patents and the calculated physicochemical informations. There are also graphical representations hydropathy values, amino acid compositions and frequencies, atomic compositions and secondary structure fractions of AAPeptide002.
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AAP ID	AAPeptide002
Peptide name	Tetrapeptide
PubMed/Patent ID	21692860,US 2020/0093799 A1
Origin	Synthetic
Source of Origin	NA
Condition addressed	Skin aging
Experiment type	In vitro, In vitro, Randomized clinical trial
Cell lines/Animal model	Primary human foreskin fibroblasts, Normal human dermal fibroblasts (NHDF)
Intervention	Cells were treated with the peptide, Topical application of the formulation
Experiment methods	MTT cytotoxicity assay, ELISA, Wound Healing Studies, Skin Atrophy Studies, Vulvovaginal Atrophy Studies, Immunohistostaining, Facial wrinkle study
Patient group	Human,Healthy human (>35 years of age)
Markers used	COL1A1
Mechanism of action	Increases the formation of procollagen, HAS-1 and fibronectin, Stimulates the production of extracellular matrix components in skin or epithelial cells

Molecular weight	389.404
Peptide length	4
Instability index	-32.575
Aromaticity	0.000
Aliphaticity	0.500
Reduced molecular extinction coeffecient	0
Oxidized molecular extinction coeffecient	0
Isoelectric point	6.001
Composition of positively charged residues	0.250
Composition of negatively charged residues	0.250
Composition of neutral charged residues	0.500
Composition of residues polar residues	0.000
Composition of residues non-polar residues	0.500
Composition of residues having cyclic side chain	0.000
Composition of acidic residues	0.250
Composition of basic residues	0.250
Composition of residues having cyclic side chain	0.000
Composition of hydroxylic residues	0.000
Composition of residue in buried solvent accessibility	0.500
Composition of residue in exposed solvent accessibility	0.500
Composition of residue in intermediate solvent accessibility	0.000

AAPeptide002 :

GEKG

Amino acid data

ProtScale

Disclaimer: Hydropathy plot is not available for AAPeptide002 as the peptide length is less than 9 amino acid residues

Atomic information

3D Structure

Structural Representation of AAPeptide002

Amino acid data

Secondary structure fraction