BGC Genome Mining Tools & Databases
Explore a comprehensive collection of tools and databases for biosynthetic gene cluster identification, analysis, and characterization. These resources complement novelBGC and provide additional capabilities for your genome mining workflows.
BGC Prediction & Identification
antiSMASH
PredictionThe gold standard for BGC identification. Detects and analyzes secondary metabolite biosynthetic gene clusters in bacterial and fungal genomes.
PRISM
PredictionPredicts and analyzes natural product structures from BGCs. PRISM 4 offers enhanced prediction capabilities.
DeepBGC
PredictionDeep learning approach for BGC detection and classification. Uses neural networks to identify biosynthetic gene clusters.
Specialized Detection and Prioritization Tools
BAGEL4
RiPPsSpecialized tool for bacteriocin and RiPP (ribosomally synthesized and post-translationally modified peptide) identification.
RODEO
RiPPsRapid ORF Description & Evaluation Online for RiPP identification and characterization.
RiPPMiner
RiPPsGenome mining tool specifically designed for RiPP discovery and analysis.
PKMiner
PKSSpecialized tool for polyketide synthase (PKS) cluster identification and analysis.
EvoMining
PhylogeneticPhylogenomic-guided mining and priortizationof natural product biosynthetic gene clusters.
ARTS
ResistanceAntibiotic Resistant Target Seeker. Priortizes BGCs encoding antibiotics based on resistance models.
Reference Databases
MIBiG
DatabaseMinimum Information about a Biosynthetic Gene cluster. The reference standard for experimentally characterized BGCs.
antiSMASH-DB
DatabaseComprehensive database of BGC annotations from antiSMASH analyses. Searchable repository of predicted biosynthetic gene clusters.
BiG-FAM
DatabaseLarge-scale BGC Gene Cluster Family database. Contains thousands of GCFs from BiG-SLiCE clustering, used for BGC classification.
BGC Comparison & Clustering
BiG-SCAPE
AnalysisBiosynthetic Gene Similarity Clustering and Prospecting Engine. Groups BGCs into gene cluster families.
BiG-SLiCE
AnalysisScalable local indexing and clustering engine for massive BGC datasets. Used in novelBGC for GCF assignment.
CLUSEAN
AnalysisCluster Network Analysis tool for visualizing and analyzing relationships between BGCs.