Other Tools

BGC Genome Mining Tools & Databases

Explore a comprehensive collection of tools and databases for biosynthetic gene cluster identification, analysis, and characterization. These resources complement novelBGC and provide additional capabilities for your genome mining workflows.

Note: The tools listed below are external resources maintained by their respective authors and institutions. Click on the links to visit their websites and learn more about each tool.

BGC Prediction & Identification

antiSMASH
Prediction

The gold standard for BGC identification. Detects and analyzes secondary metabolite biosynthetic gene clusters in bacterial and fungal genomes.

Visit antiSMASH
PRISM
Prediction

Predicts and analyzes natural product structures from BGCs. PRISM 4 offers enhanced prediction capabilities.

Visit PRISM 4
DeepBGC
Prediction

Deep learning approach for BGC detection and classification. Uses neural networks to identify biosynthetic gene clusters.

Visit DeepBGC

Specialized Detection and Prioritization Tools

BAGEL4
RiPPs

Specialized tool for bacteriocin and RiPP (ribosomally synthesized and post-translationally modified peptide) identification.

Visit BAGEL4
RODEO
RiPPs

Rapid ORF Description & Evaluation Online for RiPP identification and characterization.

Visit RODEO
RiPPMiner
RiPPs

Genome mining tool specifically designed for RiPP discovery and analysis.

Visit RiPPMiner
PKMiner
PKS

Specialized tool for polyketide synthase (PKS) cluster identification and analysis.

Visit PKMiner
EvoMining
Phylogenetic

Phylogenomic-guided mining and priortizationof natural product biosynthetic gene clusters.

Visit EvoMining
ARTS
Resistance

Antibiotic Resistant Target Seeker. Priortizes BGCs encoding antibiotics based on resistance models.

Visit ARTS

Reference Databases

MIBiG
Database

Minimum Information about a Biosynthetic Gene cluster. The reference standard for experimentally characterized BGCs.

Visit MIBiG
antiSMASH-DB
Database

Comprehensive database of BGC annotations from antiSMASH analyses. Searchable repository of predicted biosynthetic gene clusters.

Visit antiSMASH-DB
BiG-FAM
Database

Large-scale BGC Gene Cluster Family database. Contains thousands of GCFs from BiG-SLiCE clustering, used for BGC classification.

Visit BiG-FAM

BGC Comparison & Clustering

BiG-SCAPE
Analysis

Biosynthetic Gene Similarity Clustering and Prospecting Engine. Groups BGCs into gene cluster families.

Visit BiG-SCAPE
BiG-SLiCE
Analysis

Scalable local indexing and clustering engine for massive BGC datasets. Used in novelBGC for GCF assignment.

Visit BiG-SLiCE
CLUSEAN
Analysis

Cluster Network Analysis tool for visualizing and analyzing relationships between BGCs.

Visit CLUSEAN

Ready to Analyze Your BGCs?

Use novelBGC to prioritize and discover novel biosynthetic gene clusters in your genomes!

novelBGC is free to use for everybody to use, even commercially. See our license for details.