Genome Mining Prioritization Natural Products

A Compass For Biosynthetic Gene Cluster Prioritization

High‑throughput genome mining produces vast catalogs of predicted BGCs. Only a fraction can be explored experimentally. novelBGC provides a quantitative, transparent system to prioritize clusters using integrated similarity metrics and novelty cues drawn from multiple tools, guiding effort toward clusters most likely to yield new chemistry.

Investigate the biosynthetic potential of bacterial genomes without installing myriad of tools. Use a workflow which incorporates several tools and custom scripts to help you choose few candidate Biosynthetic Gene Clusters from your genome which might be novel.

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BGC Identification vs Prediction

Phylum level distribution of BGC counts from antismash database

novelBGC is free to use for everybody to use, even commercially. See our license for details.